分类： sfdrtg

In Japanese society and the global scientific community, the cloning research fraud has been raging again. According to Kyodo News, this morning, one of the authors of the fake paper, the deputy director of the comprehensive research center of occurrence and regeneration science of Japan Institute of Physical Chemistry, committed suicide.

In January this year, Japanese beauty scientist Haruko Kobao published two Nobel Prize-winning papers in Nature magazine, claiming to have discovered a brand-new method of adult animal somatic cell cloning. Sakai Yoshiki is the boss of Xiao Baofang Haruko and the co-author of the paper. However, the paper was later found to be fraudulent, and was rejected by Nature magazine, which became the biggest scandal in the international scientific community after the fraudulent incident of Hwang Woo-suk, the father of Korean cloning in 2005. Xiao Baofang Haruko himself has always refused to admit the research fraud, insisting that the experimental results are true, and only apologizes for the mistakes in citing pictures in the paper. However, the academic circles generally don’t believe Kohokata’s excuse, and the authors of the papers, including Kohokata, are under great pressure, and Sakai Yoshiki is also regarded as the main person responsible for the whole incident.

Sakai Yoshiki (middle) and Xiao Baofang Haruko (left)

Suicide of key figures in fraud scandal

Japan’s Kyodo News reported on the morning of August 5th that Sakai Yoshiki (52 years old), deputy director of the Comprehensive Research Center of Occurrence and Regeneration Science of Japan Institute of Physical Chemistry, hanged himself in the center in Kobe today. Hyogo police subsequently confirmed his death.

According to the police in Hyogo Prefecture, Sakai hanged himself after hanging a rope on the stair handrail of the research building of the research center. The police received an alarm call at 9 o’clock in the morning.

Sakai is the mentor of Xiao Baofang Haruko (30 years old), the academic leader of scientific research who wrote STAP cell papers. In January this year, he and Kohokata attended a press conference to announce the research results. At that time, STAP cells were regarded as new universal cells. After the paper was pointed out that there were violations, Sasakawa still stressed that STAP cells might exist.

Plagiarism of beauty researchers

At the end of January this year, Haruko Kobao of Japan Institute of Physical Chemistry and others published two heavy papers in the field of stem cell research in Nature, claiming that a new type of "universal cell" STAP cells can be obtained by simply stimulating somatic cells with acid bath or applying physical stress. These cells have the same characteristics as embryonic stem cells, and they can also form self-renewing stem cell lines after further operation.

This is the third method for obtaining animal embryonic stem cells, which is published after the research team of Japanese scientist shinya yamanaka and China Tsinghua University. Shinya yamanaka won the Nobel Prize for his discovery several years ago, and the preparation method of STAP is simpler.

However, in March this year, one of the co-authors of the paper, Akihiko Wakayama of Yamanashi University, asked the first author of the paper, Haruko Kobao, to provide him with STAP cells prepared from mouse cells of a certain strain. However, after a simple genetic analysis of the cells, Akihiko Wakayama found that the stem cells given to him by Haruko Kobao were prepared from mouse cells of other strains. This indicates that these cells may be contaminated.

The controversy over Xiaobaofang Haruko’s research on alleged fraud began. On April 1st this year, after investigation, the Japanese Institute of Physical Chemistry announced that the first author of the paper, Xiao Baofang Haruko, director of the research office of the Developmental Biology Center (CDB) of the Institute of Physical Chemistry, had academic misconduct such as fabrication and tampering. Although the co-authors have no academic misconduct, they are also "responsible" for failing to play a gatekeeper role. Since then, Nature has also withdrawn two papers.

As the reporter stared at all the papers published by researcher Kohokata so far, it was found that there were obvious plagiarism marks in her doctoral thesis submitted to Waseda University three years ago, and 20 of the 109 pages of papers were completely copied from the public papers of an American research institute. Moreover, the photos used in the doctoral thesis are completely consistent with the photos of this universal cell experiment, which were copied from the website of a biological company.

This incident has caused a great condemnation of academic fraud in the global academic circles, and the Japanese government has also begun to purge its own scientific community. On April 14th, at the highest science policy organization in Japan — — At the meeting held by the Council for Science and Technology Policy (CSPT), an eight-member committee group called for the establishment of academic integrity of researchers, and called for the establishment of a series of prevention and response measures against academic fraud at the institutional level to rebuild public confidence in science.

Xiao baofang haruko apologized for the falsification of the paper.

Kohokata was exposed to consider suicide.

On April 9 this year, Xiao Baofang Haruko was forced to face the public on the issue of fraud. 30-year-old Xiao Baofang Haruko cried tears in front of hundreds of reporters at a news conference recorded on TV, but she insisted that she did not tamper with the data to falsify the experimental results.

She claimed that she didn’t agree to withdraw the research, saying that she had "confirmed this fact many times" and vowed that if she was allowed to return to any laboratory, she would prove that what she said was true.

Kohokata only apologized for citing several incorrect pictures in his paper and modifying one picture in the report. She said that her mistakes were lack of experience and poor academic skills, and she called on her colleagues to continue the research.

Kohokata said that he was opposed to withdrawing the paper published in the journal Nature, because it would give the international academic community the impression that the research was incorrect.

She also said at the press conference, "I can’t sleep well every day and my mood is getting worse." Some reporters even reported that in the face of unanimous accusations from the academic circles, Kohokata may be hard-headed, and may have the possibility of self-injury or suicide.

Sakai Yoshiki is behind the scenes?

Xiao Baofang Haruko also has many sympathizers. It was pointed out that there were eight authors in the fake papers, and the real main publication was not researcher Kohokata, but Fang Shu Sasui, deputy director of the Comprehensive Research Center for Regenerative Science of the Institute of Physical Chemistry.

Some media pointed out that since Professor shinya yamanaka of Kyoto University won the Nobel Prize in 2012 for his successful research on IPS cells, Japanese national attention has been focused on Professor Yamanaka. According to the research results, Professor Yamanaka’s achievements are far more than those of Sakai Fangshu. As an important expert in this field, he is definitely uncomfortable. In order to compete with Professor Yamanaka, the Institute of Physical Chemistry decided to launch the "Beauty Scientist" route in Kohokata to compete with Professor Yamanaka. Moreover, there is competition in the Institute of Physical Chemistry, and the research funding will be cut without certain achievements.

Hastily announcing immature results and finally failing is also the best explanation for this commotion. Poor researcher Kohokata has been criticized by Japanese researchers all over the country. As a result, she can’t do any more research, because her image is not good, and there will be no co-researchers. Even if she publishes it alone, no one will be interested in her. Now, only the existence of STAP cells is definitely proved, which is the best means to bring them back to life.

Some media even claimed that the relationship between Sakai Yoshiki and Xiao Baofang Haruko was ambiguous. Because after graduating from Haruko University, Xiaobaofang has a much smoother career path than graduates from many other famous universities. I got a five-year researcher’s contract with the Institute of Physical Chemistry very early, and was sent to Harvard University for research with the support of a scholarship. Come back and become a researcher of the project.

Although Sakai Yoshiki has a wife and a family, she is particularly close to Xiao Baofang Haruko. Some people say that they saw the two of them making out in the research room. So many people are saying that this research scandal is not only academic fraud, but also the shadow of erotic trading and interest trading.

　　The industry believes that a consumption tax on luxury cars in the retail sector will not only reasonably guide consumption, but also increase fiscal revenue.

　　The Ministry of Finance and the State Administration of Taxation issued a notice yesterday, saying that in order to guide rational consumption and promote energy conservation and emission reduction, with the approval of the State Council, consumption tax will be imposed on ultra-luxury cars. This regulation will be implemented as of December 1, 2016.

　　Tax will be increased by 10% on the sales of ultra-luxury cars.

　　The notice pointed out that the sub-tax item of "super luxury cars" will be added under the tax item of "cars". The scope of collection is passenger cars and light commercial buses with a retail price of 1.3 million yuan (excluding value-added tax) and above, that is, ultra-luxury cars in the sub-tax items of passenger cars and light commercial buses. For ultra-luxury cars, on the basis of the consumption tax levied at the current tax rate in the production (import) link, the consumption tax is levied at the retail link, and the tax rate is 10%. The notice makes it clear that the units and individuals that sell ultra-luxury cars to consumers are taxpayers in the retail link of ultra-luxury cars.

　　10% consumption tax will not be levied on the sold vehicles for filing within 5 days.

　　For distribution channels, will the vehicles that have signed automobile sales contracts before November 30 be affected by the adjustment of the consumption tax on ultra-luxury cars? It is understood that for ultra-luxury cars that have signed automobile sales contracts before November 30 (inclusive), but have not delivered the real thing, taxpayers will file the signed automobile sales contracts with their competent tax authorities within 5 working days from December 1 (inclusive). According to the notice information, the retail consumption tax with the tax rate of 10% will not be levied for those who are filed according to the regulations, and the retail consumption tax will be levied if they are not filed and not filed within the prescribed time limit.

　　It is difficult to manage the tax after tax collection.

　　According to the information, when the consumption tax was implemented in 1994, it included automobile tax items. In the consumption tax reform in 2006, the automobile consumption tax was adjusted. It is understood that the current car tax items are divided into two categories: passenger cars and medium and light commercial buses. Among them, the larger the cylinder capacity of passenger cars, the higher the tax rate of consumption tax, and the tax rate ranges from 1% to 40%. Passenger cars with a cylinder capacity of more than 4 liters will be subject to a consumption tax rate of up to 40%. The consumption tax rate of 5% is applicable to medium and light commercial buses. The taxation link is in the production and import links.

　　According to industry analysts, a consumption tax will be levied on luxury cars in the retail sector, with the aim of reasonably guiding consumption and increasing fiscal revenue.

　　"The consumption tax collection link is changed to the retail link. The advantage is that the final selling price of goods can be taxed, and the tax base is obviously expanded, which can increase fiscal revenue and reasonably guide consumption, but the challenge is that the collection and management are difficult." The above analysis pointed out that the relevant departments took luxury cars as a breakthrough and imposed a consumption tax on the retail sector, which is also based on the fact that there are not many 4S retail stores in China compared with retail stores such as tobacco and alcohol, and it is relatively easy to control. This will provide experience for the next stage of other tax items to move back.

　　Text/reporter Ren Xiaoyuan

　　affect

　　The actual impact on car buyers will not be great.

　　At present, the models with more than 1.3 million yuan are basically ultra-luxury car brands such as Bentley, Maserati and Porsche. In addition, some brands such as BMW X6, BMW 7 Series, Mercedes-Benz GL Series and Audi A8 have reached this level. Therefore, the influence of the new consumption tax policy is relatively small and fixed. But at present, it should not have much impact on the sales in this market.

　　China’s automobile consumption tax was established in 1994, and the latest automobile consumption tax reform was in 2008. The tax rate for passenge cars with displacement of 3.0L to 4.0L is raise from 15% to 25%, and that for passenger cars with displacement of 4.0L is raised to 40%. Reduce the consumption tax rate of small-displacement passenger cars, and reduce the tax rate from 3% to 1% for passenger cars with displacement below 1.0L This time, the tax rate will be increased by 10% for ultra-luxury cars with a price of more than 1.3 million yuan. This adjustment mainly affects the sales of imported vehicles.

　　According to the previous consumption tax policy, the tax rate of ultra-luxury cars is basically 40% high-end. Compared with the consumption tax of 40%, the current 25% tariff and 17% value-added tax have become small heads, so for luxury cars with a price of several million yuan, the consumption tax itself is an important factor to increase the difference between domestic and foreign car prices. Judging from the new policy introduced this time, an additional 10% consumption tax will be imposed on ultra-luxury cars with a price of more than 1.3 million yuan, which will not have a great impact on car buyers. In fact, many 4S shops will basically increase the price of ultra-luxury cars by 100 thousand to several hundred thousand yuan above the manufacturer’s guide price before they can pick up the car, and most car buyers also acquiesce to this.

　　Text/reporter zhangqin

　　extend

　　Whether the purchase tax on small-displacement vehicles will continue to be halved is inconclusive.

　　In fact, in the automobile consumption, there is also an essential expenditure, which is the purchase tax. China’s automobile purchase tax rate is set at 10%, which accounts for a large proportion in the cost of car purchase. However, at present, China has adopted a preferential policy of halving the purchase tax for small-displacement vehicles of 1.6 liters or less, that is, it is levied at 5% of the vehicle price, which has played a significant role in promoting the consumption of small-displacement vehicles.

　　The preferential policy of halving the purchase tax on small-displacement vehicles has been implemented since October 1, 2015. According to the plan at that time, the policy will expire on December 31, 2016, which means that there is still a whole month left. Up to now, there is no official explanation on whether the preferential policy of halving the purchase tax will continue, and more is speculation from outside. It is also reported that various departments at the government level have different opinions on whether to continue this policy. Earlier, some media reported that on November 1, the National Development and Reform Commission, the Ministry of Communications, the Ministry of Finance and other ministries and commissions held departmental meetings to study whether to continue this policy, but no news came out since then.

　　The data shows that the prices of 1.6-liter and below displacement models are mostly concentrated below 200,000 yuan. According to the current preferential policies, the purchase tax for bicycles ranges from 3,000 to 10,000 yuan. Once this policy is cancelled next year, it is likely to drive the sales ratio of models above 1.6 liters to increase in a short time. According to the data of China Automobile Association, in 2015, the sales of passenger cars of 1.6 liters and below reached 14,508,600, an increase of 10.38% over the same period of last year, which was higher than the overall growth rate of passenger cars and accounted for 68.6% of the sales of passenger cars.

　　Text/reporter zhangqin for the picture/vision china

This article was first published in the film industry. Welcome to pay attention (WeChat search filmmore).

　　　　 The news of the postponement of popular blockbusters is endless. From last summer’s troika to this year’s Spring Festival’s three strong films, the screening time has been extended, and the box office champion of Chinese films has been postponed for three months at once. In the eyes of the general audience, the postponement means that it can be seen in the cinema one month after the film is released. However, in the eyes of the industry, the specific process of key extension is the most important. Why can a movie be released for as long as four months? Is the existence of this mechanism reasonable? This article will take you through all aspects of key extension.

　

What is the key extension? You can’t show a movie until you have a key. You don’t have to pay for an extension.

　

　　　 For the general audience, the word key is unfamiliar. What is a key? This should start with the film screening. The movie will be made into a copy, and it needs to be connected to the server before it can be read. The key is similar to the activation code, which allows the server to successfully read the movie in the copy. At this time, the projector can play the movie, and it cannot be shown without the key.

　

　　　 So where did the key come from? According to a senior person who has been engaged in distribution for many years, most of the current keys are made by China Film Digital Film Development Co., Ltd. (hereinafter referred to as China Digital Film Development Co., Ltd.) and Huaxia Film Distribution Co., Ltd. (hereinafter referred to as China). These two companies actually play the role of agents between the issuer and the cinema, and the issuer can save manpower and material resources through their communication and settlement with the cinema. Therefore, we will see the names of these two companies in many documents with extended keys.

　

　　　 After the key is made, it will be uploaded to the network and downloaded by each theater. The validity period of the key is one month, that is, we often say that the film screening period is one month. After the expiration, the cinema server will no longer be able to read the movies in the copy. At this time, if you still want to show, you need to postpone the key.

　

　　　 When a movie wants to be postponed, do you still have to pay a fee? The answer is no, Zhu Dawei, vice president of Stellar Pictures, Qin Wei, vice president of Beijing An Shi Ying Na Film Distribution Company (hereinafter referred to as An Shi Ying Na) and many other people in the industry have confirmed this, but they don’t need to pay for the extension of the key.

　

Is there a standard for key extension? Domestic films are flexible to operate and imported films are difficult to judge.

　

　　　 Since it doesn’t cost money to extend the key, isn’t it an extension if you want? You can postpone it at any time or for as long as you want. The answer is still no.

　

　　　 According to the distributor who has operated many imported films, it is true that there is no explicit stipulation in the mainland about which films can be postponed and which ones can’t. Generally speaking, domestic films are very flexible in operation. "Just tell the distribution company, such as China Digital, through them to tell the cinemas that we have extended the key, and everyone can still use it. That’s it." Of course, the so-called "let me know" actually needs to be presented in written form, but domestic films will basically not encounter any problems and there is no limit.

　

　　　 But this is not the case with imported films. Zhu Dawei, vice president of Stellar Films, said that imported films need to apply to the Film Bureau for extension. According to the senior distributor, after the imported film is submitted, it depends on whether it will be rejected.

　

　　　 There are indeed many domestic films and some imported films in the history of mainland film. For example, the one in 2010, which was released on January 4, was postponed until March 14, when it was released for more than two months, is very rare in imported films. Released on April 10, 2012, it was extended for another month when the key expired, and finally the box office exceeded 1 billion.

　

　　　 Looking back carefully, most of the key extension time is within one month, and it is really surprising that the Mermaid has been extended for three months at once. Is it arbitrary to extend the time? The answer this time is yes.

　

Is there a time limit for extension? The film is completely independent, and most of them do not exceed one month.

　

　　　 After the key expires, how long you want to extend it is really up to the film, whether it is a week or a month, and no one interferes. The three popular films in the Spring Festival were postponed for one month, 12 days and released on March 20th, except Mermaid, which was postponed for three months. At present, there is no specific extension, and there is no strict regulation on when to apply for an extension.

　

　　　 Qin Wei, vice president of Ann Shi Ying, told us that in theory, five working days before the start of the extension, they would communicate with the key maker who often cooperated, but there was no big problem earlier or later, and the time was more flexible. Moreover, the extension notice of "Journey to the West’s Monkey King Thrice Defeats the Skeleton Demon" released by Ann Shi Ying was issued on February 18. The reason why the extension notice was released ten days after the film was released was because both the film producer and the publisher had enough confidence. "We felt that the reputation was good and we wanted to take a long-term screening from the beginning."

　

　　　 After the issuance direction of China Digital or Huaxia proposed to extend the key, the two companies completed it relatively quickly. "Now, if you follow the process, you can go down in two days. In fact, China Digital also has a competitive relationship with China, and everyone has to compete for services." The veteran of the distribution industry said. According to Qin Wei, sometimes it doesn’t take two days. "It can be made in half a day, which is faster."

　

Next page:What kind of movie will be postponed? Blockbusters usually delay the box office as the driving force.

As the Spring Festival approaches, law enforcement officers of the Yushui District Market Supervision Bureau in Xinyu City, Jiangxi Province conduct on-site rapid detection of vegetable pesticide residues at Guanxia Smart Farmers Market. Photo by Liao Haijin/Bright Picture

A college student food festival was held in Shanghai. The picture shows the "fleshy" Mu Si cake as a dessert in the dining hall of Shanghai Ocean University. Xinhua news agency

Citizens and tourists visit the Chongqing New Year Food Festival. Xinhua news agency

Villagers in Kangzhuang Village, Qukou Town, Xianghe County, Hebei Province are drying red and white sausages. Xinhua news agency

　　Is "artificial meat" edible? Is online celebrity food reliable? Are probiotics really useful? What foods have you paid attention to in the past 2019? What troubles have they brought you? Food safety concerns people’s health and life safety. At the "Media Communication Meeting on Scientific Interpretation of Food Safety and Health Hotspots in 2019", which was directed by China Association for Science and Technology and hosted by chinese institute of food science and technology recently, experts combed and interpreted the hot events of food safety that the public paid attention to in the past year, and made suggestions for food safety supervision by popularizing food safety knowledge through examples. This edition extracts some hot topics to interpret.

"artificial meat"

Scientific and technological problems to be solved, standards and regulations to be improved.

　　Interpretation expert: Wang Shouwei (Director of China Meat Food Comprehensive Research Center and Dean of Beijing Food Science Research Institute)

　　"Artificial meat" is synonymous with foods that are not naturally produced and have a similar taste to meat. It is usually divided into two categories: vegetable protein meat and cell cultured meat. The emergence of "artificial meat" on the one hand is to meet the rapidly growing meat demand of consumers, on the other hand, it provides a way to effectively reduce the land occupation of animal husbandry, the use of water resources and greenhouse gas emissions, and solve the problems of environmental protection and sustainable development.

　　In recent years, the processing technology of vegetable protein meat is becoming more and more mature at home and abroad, and many enterprises have developed vegetable protein meat products with vegetable protein as raw materials. The research on using animal stem cells to produce cells to cultivate meat has also made great progress, and many enterprises have announced that they can develop cells to cultivate meat in the laboratory. Vegetable protein meat has great market potential and a high degree of commercialization. In the future, developing products more similar to real meat has become a direction for the food industry and scientific and technological circles.

　　In the innovation and development of "artificial meat", it is necessary to increase scientific and technological input and solve the existing scientific and technological problems of "artificial meat". For example, research on the formation mechanism, raw material supply and processing technology of vegetable protein meat should be carried out to build a new research and development system. In the process of industrialization, we pay attention to improving the flavor, texture and nutrition of products, and constantly meet the increasingly diversified needs of consumers. Carry out research on the basic theory and key production technology of cell-cultured meat, and establish a production technology system of cell-cultured meat suitable for human food manufacturing.

　　While innovating and developing, adhering to product quality and safety is the foundation of the development of "artificial meat". It is suggested that the new ingredients and new production technology added in the production of "artificial meat" should be systematically evaluated for safety, and an independent standard system and an objective supervision system should be formed in the evaluation of product safety and nutritional components, so as to promote the benign development of the industry.

　　Scientific and rigorous standards are the cornerstone of the healthy development of the industry. In China, the development momentum of vegetable protein meat industry has been formed, and the product categories are relatively mature, but the existing laws and regulations are not suitable for product innovation and industry development; The development of its standard should be carried out as soon as possible, and the definition, classification method and production technology should be clearly defined, which will provide convenience for government supervision and provide reference for the direction of production and innovation of products in the industry. In addition, the research and development of cell-cultured meat in China is still in its infancy, but the development speed is very fast, and the research on standards and supervision methods has just begun; The division of supervisory responsibilities and division of labor system should be clarified, and a strict system of standards and laws should be formed. In addition, public science popularization should be carried out to guide consumers to correctly understand and rationally consume "artificial meat".

Online celebrity food

Strictly guard against the transformation of "red and black"

　　Interpretation expert: Ma Guansheng (Head of the Department of Nutrition and Food Hygiene, Peking University College of Public Health)

　　Some sellers make use of social media’s special publicity and marketing methods to dress up homemade food as "online celebrity" food, which is popular in the circle of friends. From home-made delicious food to home-brewed fruit wine, from morning tea snacks to midnight snacks, from beauty soup to dietary remedies, there are all kinds of foods in the circle. Online food attracts waves of consumers with its novel appearance, photos or taste. However, when consumers buy food, they often ignore the quality of the food itself, including raw materials, production date, shelf life and production address.

　　Due to the special sales channels (such as WeChat circle of friends, micro-stores), online celebrity food has some problems, such as difficult management and lack of effective supervision mechanism. Taking the incident of "there is no milk in milk tea" in online celebrity as an example, China’s national standard "Tea Beverage" (GB/T 21733-2008) defines milk tea drinks and milk tea-flavored drinks as liquid drinks prepared by taking water extract of tea or its concentrated solution and tea powder as raw materials and adding one or more of milk or dairy products, sugar and/or sweeteners, edible milk flavor essence, etc. Although there is a requirement for the protein content of milk tea in this standard (≥ 0.5%), but milk or dairy products are still only one of a variety of optional ingredients, not a hard requirement. Therefore, due to the lack of clear standards for existing milk tea, there is an embarrassing situation that "milk tea does not contain milk", which increases the maneuverability of merchants and brings blind spots to food safety supervision.

　　It is suggested to improve the supervision mechanism and clarify the responsibilities and supervision methods of all parties in the business activities of non-traditional foods such as online food sales. At the same time, strengthen regular sampling and random inspection, and urge network platforms and production operators to implement the main responsibility. Strike hard at illegal food safety behaviors in online sales, strictly investigate and deal with behaviors such as "brushing the bill" and "false comments", and protect consumers’ rights and safety with strict supervision.

　　Online celebrity food is mainly sold through the online platform, so the online platform should assume the responsibility of screening and supervision. The network platform should establish a mechanism to help the superior and limit the inferior, strictly control the entry threshold of merchants, inspect and regularly review their retail qualifications and relevant licenses for selling products, and prevent counterfeit and shoddy foods from being sold on the network platform. Food enterprises and individual food producers should strengthen the construction of industrial chain safety, ensure the safety and traceability of product sources, make the product chain clear, and prevent and control risks. As consumers themselves, they should constantly improve their health literacy and food safety literacy, make rational purchases, and not blindly "chase after the red".

probiotics

The efficacy has the specificity of strains and people.

　　Interpretation expert: Chen Wei (Academician of China Academy of Engineering, Chairman of Probiotics Branch of chinese institute of food science and technology, Vice President of Jiangnan University); He Guoqing (Vice Chairman of chinese institute of food science and technology Probiotics Branch, Professor of Zhejiang University)

　　Probiotics have a strict definition: they must be living microorganisms, which are beneficial to the health of the host when ingested in sufficient quantities. Moreover, the health function of probiotics should be based on scientific and rigorous clinical trial evaluation and evidence-based medical evidence. At present, tens of thousands of published academic papers have studied the functions of different probiotic strains, confirming that the core function of probiotics is to improve the health of human gastrointestinal tract. In addition, in vitro experiments such as cell model, animal experiments and human experiments show that probiotics may have potential beneficial functions to improve metabolism and nervous system. However, in vitro experiments and the actual human digestive system are completely different worlds, and the results of in vitro experiments can never be used to claim the functions of probiotics. Animal experiments can be used as a reference, but it needs to be confirmed by large-scale and deeper human or clinical experiments.

　　It is a long-term, rigorous and scientific process for human beings to explore the efficacy of probiotics. At present, there are various probiotic products with claimed functions on the market. However, it should be emphasized that the academic community has reached a consensus that the core function of probiotics is to improve gastrointestinal health.

　　Generally speaking, the mainstream probiotic strains in the market are all isolated from healthy people and fermented foods with a long history of safe use. Most of them are considered as non-pathogenic symbiotic microorganisms, and their safety has been recognized by authoritative organizations. Of course, for sick individuals, such as patients with severe infection or immunodeficiency, they should be used with caution or consult a doctor.

　　It should also be noted that the efficacy of probiotics has the specificity of strains and people. There are differences in probiotic efficacy among different strains; There are also differences in physiological regulation of probiotics among different hosts. Therefore, in the future, we should confirm the relevant probiotic functions at the strain level, judge and apply the individual functions of probiotics according to the individual characteristics of different hosts, and pay attention to personalized precise nutrition. Of course, the industrial application of probiotics must also be verified by scientific and rigorous processes. For example, the species, even the genetic composition and basic physiological and biochemical characteristics of the strain are first studied, and then the adaptability, safety and probiotic characteristics of the strain are evaluated in turn, and finally the probiotic dosage and probiotic combination with satisfactory efficacy are selected.

　　In addition, consumers should choose probiotic-related products scientifically and reasonably. For lactic acid bacteria drinks, consumers should pay attention to distinguish product types when purchasing. According to the relevant standards in China, the labels of lactic acid bacteria drinks should be marked with live bacteria (non-sterilization) or non-live bacteria (sterilization), and they can be distinguished by labels when purchasing. When consumers buy yogurt, they should keep it reasonably according to the label. Low-temperature yogurt should be sold in cold storage. When they return home after purchase, they should put it in the refrigerator as soon as possible and drink it in time to ensure its strain activity.

　　Probiotics have individual differences in their effects on health, and there is no "all-purpose" probiotic strain, which is suitable for everyone and all physical conditions. We should further strengthen the popular science education of consumers, popularize the professional knowledge of probiotics and clarify the scientific concept of "quantity" of probiotics, so that consumers can rationally choose probiotic products.

Self-heating food

It is necessary to cross the safety hurdle of "self-heating package"

　　Interpretation expert: Lu Fuping (Vice President of chinese institute of food science and technology and Vice President of Tianjin University of Science and Technology)

　　Self-heating food is a product that heats food with flameless self-heater and quickly reheates it to edible state. In recent years, a series of self-heating products represented by self-heating hot pot have developed rapidly. Besides the common self-heating hot pot and self-heating rice, there are also self-heating porridge, noodles, rice noodles, soup, etc., which are diverse and meet the urgent needs of consumers for hot food in more consumption scenarios.

　　Although the safety of self-heating food is generally controllable, the safety risk of "self-heating package" should be paid full attention to. Since self-heating food uses the chemical reaction between heating agent and water to generate heat to heat the food. Occasional phenomena such as "self-heated food rupture" or "unstable temperature of self-heated food" have aroused people’s concern about the safety of self-heated food.

　　Under the current self-heating technology in China, the chemical self-heating package used for self-heating food is mostly magnesium/iron for military use and aluminum-water for civilian use. No matter what kind of heating package, a small amount of hydrogen will be produced when heating. If individuals eat or a small number of people gather to eat, even in a closed environment, the amount of hydrogen generated by the heating of the heating package is far from the limit that can cause explosion. Under normal circumstances, the normal products will be eaten according to the normal operating procedures, and there will be no risk and safety problems such as cracking. However, if people eat a lot of self-heating food at the same time in a closed environment, or if the vent hole on the self-heating food packaging box is blocked, there may be potential safety hazards, which need to be paid full attention to.

　　It is suggested to increase the research on the safety of self-heating package and develop a self-heating package with high efficiency and good safety. By developing energy-efficient formula and new heating device, the generation of hydrogen and water vapor can be controlled or reduced, the demand for energy efficiency release and utilization can be improved, and the safety level can be improved. Develop a new type of physical self-heating device, use renewable energy and reduce pollution. In addition, it is necessary to enhance the effectiveness and support ability of the self-heating device in various scenarios.

　　The rapid development of self-heating food industry has attracted a large number of enterprises to join. However, due to the imperfect standards and specifications of self-heating food, the enterprises that have joined the self-heating food industry are mixed, which seriously affects the healthy development of the industry. At present, only the group standard "Self-heating Convenient Cuisine Products" issued by China Business Federation in 2017. From the perspective of regulating the industry, self-heating food needs more stringent standards to ensure its healthy development. It is understood that the industry is actively exploring how to establish a unified standard, for example, by standardizing the chemical composition and proportion, heating intensity, hydrogen production and other indicators contained in self-heating food heating packages, and making clear requirements for the treatment of final waste, so as to improve the entry threshold of the industry and standardize the healthy development of the industry.

Special medical food

Not for everyone

　　Interpretation expert: Ren Fazheng (Academician of China Academy of Engineering, Vice Chairman of chinese institute of food science and technology Probiotics Branch, Professor of China Agricultural University)

　　Special medical food is formula food for special medical use, which is specially processed and prepared to meet the special needs of people with limited eating, digestive and absorption disorders, metabolic disorders or specific disease States for nutrients or meals. It also has a very strict classification, which is currently divided into two categories: people aged from 0 months to 12 months and people over 1 year old.

　　On the basic functions of special medical food — — At present, there is a broad consensus on nutritional support, including improving the treatment and rehabilitation effect, shortening the course of disease, reducing medical expenses, increasing the turnover rate of hospital beds, and reducing the readmission rate, which can be solved through nutritional support and special medical food. The World Health Organization has proposed that if more money is invested in nutrition and health care, less 8.5 yuan can be spent on treatment and the cost of rescue in 100 yuan can be saved. It can be said that the nutritional support function of special medical food is indispensable in clinic. Of course, it can’t replace drugs.

　　Special medical food is a new industry in our country, and our government attaches great importance to it, and has made very strict management regulations at the beginning of the industry development. Special medical food should be registered by the food safety supervision and administration department of the State Council, and the formula of special medical food should be based on the research results of medicine and nutrition, and its safety and clinical application effect need to be scientifically confirmed.

　　According to news reports, some illegal enterprises produce ordinary solid drinks, pass off as special medical milk powder and mislead consumers. This kind of behavior belongs to false propaganda, which should be severely cracked down and strengthened management. In addition, when the special medical food is registered and put on record, the product formula and production technology are strictly regulated. Food enterprises should produce special medical food according to the registered formula, and cannot produce special medical food without obtaining the registered formula and production license.

　　The demand emphasizes that special medical food is special and not suitable for everyone. Moreover, different special people need different special medical foods. We should strengthen the popularization of special medical food, let consumers know its particularity and eat it according to the doctor’s advice.

Reduce salt, oil and sugar

Science and technology lead, scientific implementation

　　Interpretation expert: Chen Junshi (Academician of China Academy of Engineering, General Consultant of National Food Safety Risk Assessment Center)

　　The diet of Chinese residents is high in salt, oil and sugar. "Three reductions" is not an isolated matter, it is an important part of the whole reasonable diet. Whether it is the government supervision department, food industry or consumers, it is necessary to raise awareness and establish the concept of "reasonable diet".

　　Carrying out the "three reductions" action is not a matter for any department or enterprise, but should be coordinated and promoted by all parties. The government should formulate corresponding policies to lead the "three reductions" action, and catering and food processing enterprises should provide diversified products with different levels of salt, oil and sugar for consumers to choose by reducing the use of salt, oil and sugar. Residents gradually reduce the use of salt, oil and sugar in their daily cooking.

　　In particular, the food industry and catering industry should accelerate the transformation and upgrading of nutrition according to the health needs of consumers, and take the initiative to take measures to reduce the use of salt, oil and sugar in food. This requires increasing scientific and technological support, laying a solid scientific foundation, solving the problems such as product flavor change and shortened shelf life that may be caused by "three reductions", innovating and developing new foods, and leading a healthy transformation with science and technology. In addition, there are different dietary nutrition problems in different regions and different groups of people, so nutrition science education should be targeted and reflect differentiation. Nutrition intervention should be precise, and the implementation of policies should be based on science and practical. Focus on guiding enterprises to provide more differentiated products for consumers to choose, and guide consumers to choose products that suit them reasonably.

　　The action of "three reductions" needs to be carried out step by step in line with China’s national conditions, instead of "eating a fat man at one breath". It takes time to change people’s tastes, not quick. The improvement of cooking, methods and food processing technology also takes time, which cannot be achieved overnight, and should be carried out step by step in accordance with scientific laws. The transformation of consumer health concept needs long-term positive guidance and popularization of scientific knowledge. Therefore, the implementation of the "three reductions" action must be gradual, and various problems must be solved step by step.

Food fraud

Counterfeiting detection technology needs to be upgraded

　　Interpretation expert: Wu Yongning (Chairman of chinese institute of food science and technology Food Authenticity and Traceability Branch, Technical Chief of National Food Safety Risk Assessment Center); Chen Ying (Vice President and Chief Engineer of China Academy of Inspection and Quarantine)

　　Food quality, food safety and food truth are three attributes of food. The authenticity problems such as food fraud and forgery exist at home and abroad. For example, as the saying goes in China, "selling dog meat by hanging sheep’s head" and the "horse meat passing off as beef" that happened in Europe a few years ago. The World Health Organization once pointed out that apart from food-borne diseases, more and more food fraud and food fraud problems need to be paid attention to.

　　Ensuring the authenticity of food is not only to protect public health, but also a necessary measure to curb the market chaos of "bad money drives out good money", standardize the market competition order and boost food consumption confidence. At present, China has basically met the public’s requirements for the quantity and quality of food, and the concern for food safety has reached a higher level. However, for a long time, the investment in food authenticity technology is relatively lacking, and it is difficult to guarantee the scientific supervision of "food authenticity". If food fraud is "a magic height of one foot", then the detection technology of counterfeit identification must be "a magic height of one foot".

　　It is suggested to increase the scientific and technological investment in food authenticity research and overcome the technical difficulties and supervision problems of food authenticity. At the same time, speed up the transformation of technical standards of food authenticity, formulate corresponding detection methods and standards, and provide technical support for scientific supervision of food authenticity in China.

　　(This edition of the article was compiled by our reporter Chen Haibo)

Although Audi Q4 e-tron is not excellent, it can reach the mainstream level of the same level. The strength of the car still needs to be understood before we know, so let’s take a look.

Let’s take a look at the appearance of the Audi Q4 e-tron. The front of the Audi Q4 e-tron looks very calm and deep. Then the fashionable headlight design is adopted, which is very sporty. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, delayed closing, rain and fog mode and so on. Come to the side of the car, the car body size is 4588MM*1865MM*1626MM, the car uses rounded lines, the car side gives people a very avant-garde feeling, with large-size thick-walled tires, eye-catching shape. In the rear part, the overall shape of the rear part echoes the front face, the taillight style is more individual, and the overall layout is impressive.

In terms of interior, the interior of Audi Q4 e-tron presents a concise design style, and the overall design atmosphere is still in place. The steering wheel of the car is very in line with the interior style, made of genuine leather and has a high palm fit. Let’s take a look at the central control. The design of the center console is reasonable, which makes the interior style impressive, and the details are still in place. The interior feels good. Let’s take a look at the dashboard and seats. The dashboard design is remarkable and gives people a very lovely feeling. The car uses a mix of leather/suede seats, and the seat wrapping is in place and the comfort is acceptable.

Audi Q4 e-tron matching gearbox, 100 km acceleration time is 6.8s, and the power is completely OK for daily use.

Equipped with car networking, driving mode selection, remote control key, rear wiper, interior atmosphere light and other configurations, the configuration has reached the mainstream level of the same level.

The model class introduced today is the most considered class when many people buy their first car, mainly because the size of this class is moderate and the price is reasonable. If you are interested, you might as well experience it.