Fertility assessment helps women better understand their fertility potential.

Authors: Deputy Chief Physician Zhu Xiaodan, Department of Obstetrics and Gynecology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine.

At present, the global fertility problems are increasing day by day, and the overall fertility of women is on the decline. Women are facing various pressures in modern society, including occupational pressure, family pressure, social expectations, and the unhealthy lifestyle that follows, which makes the fertility of contemporary women decline more and more "younger". At present, the incidence of infertility is as high as 10%~18%. In 2023, the birth rate in China was as low as 6.4‰.

National birth rate

In the reproductive endocrinology clinic, patients often ask: How is my fertility? Can you still be born? Faced with such a question, today, let’s talk about this topic.

As we all know, to complete a successful pregnancy, women need the cooperation of the whole reproductive system and all organs of the whole body. Therefore, the evaluation of female fertility is divided into three parts: the first part is the evaluation of ovarian reserve function, the second part is the evaluation of the structure and function of uterus and fallopian tube, and the third part is the evaluation of general state.

First, the ovarian reserve function

The ovarian reserve function of women refers to the quantity and quality of eggs, that is, the "inventory" of follicles with growth and development functions. The number of follicles in women has been determined at birth and is non-renewable. With the increase of age and the progress of menstrual cycle, the number of eggs gradually decreases. So how do we evaluate how much "inventory" there is in the ovaries?

1. Age

Age is the primary factor to evaluate fertility, and the best reproductive age for women is 23~32 years old. With the increase of age, fertility gradually decreases, pregnancy rate and live birth rate decrease, and abortion rate increases. With the increase of age, ovarian function declines irreversibly, and the number of follicles and the quality of eggs decrease. Age-related abnormal vascularization, oxidative stress and free radical imbalance in the ovary will lead to the decline of oocyte quality, which will lead to fertilization failure or abnormal embryo development.

The picture comes from the Internet.

2. Basic follicle stimulating hormone (bFSH)

BFSH is the level of serum FSH on the second to fourth day of menstruation, and it is one of the indexes to evaluate ovarian reserve function. The main reasons for the increase of bFSH level are the aging, the decline of ovarian function, the decrease of E2 secretion, the weakening of negative feedback on hypothalamus-pituitary-ovarian axis, and the subsequent increase of FSH. When the serum level of bFSH is higher than 10u/L, the ovarian reserve function is decreased, and when the serum level of bFSH is higher than 18u/L, the live birth rate is almost zero.

3. Basic estradiol (bE2)

BE2 refers to the level of serum E2 on the 2nd to 4th day of menstrual cycle, which can be used as an index to evaluate ovarian reserve function. When the bE2 value is more than 74.9 pg/ml (274.134 pmol/L), the ovarian function is decreased or the pregnancy outcome is poor when in vitro fertilization (IVF) is performed, and the number of embryos obtained is small.

4. FSH/LH (follicle stimulating hormone/luteinizing hormone) ratio

FSH/LH ratio can be used as an index to reflect ovarian function, and can also be used as a sign of ovarian response to gonadotropin to predict pregnancy outcome. When FSH/LH > 2, it is suggested that the ovary may have a bad reaction to gonadotropin in assisted reproductive technology. When FSH/LH > 3.6, the ovarian function is obviously decreased, and the cancellation rate of IVF ovulation cycle is high.

5. Anti-Miller hormone (AMH)

AMH is mainly produced by primary follicles, preantral follicles, sinus follicles, etc. It regulates the growth and development of follicles and is not regulated by hypothalamus-pituitary-ovary axis. As a reliable index of ovarian reserve function, it can be detected on any day of menstrual cycle. Serum AMH concentration was negatively correlated with age. AMH value reaches its peak in adulthood (about 25 years old), generally drops significantly after 36 years old, and approaches zero when approaching menopause.

6. Inhibin B(INH-B)

INH-B appears from the pre-antral follicular phase and is regulated by FSH. INH-B level, as a direct index to predict ovarian reserve function, reflects ovarian reserve. On the third day of menstruation, the blood INH-B < 45 ng/L indicates that ovarian function is decreased.

7. Sinus follicle count (AFC) and ovarian volume

AFC, ovarian volume and ovarian interstitial blood flow parameters can be used as evaluation indexes of ovarian reserve function and responsiveness. AFC is significantly correlated with age and basic hormones. With age, the number of follicles decreases exponentially. Ovarian volume can reflect the number of follicles and the situation of ovarian reserve pool from another angle. With the increase of age, ovarian function declines and ovarian volume shrinks. The most commonly used parameters of ovarian stromal blood flow are the peak velocity of ovarian stromal blood flow (PSV) and resistance index (RI). High PSV and/or low RI indicate that the ovarian interstitial blood supply is abundant and the ovary responds well to gonadotropin.

Second, the evaluation of the structure and function of reproductive tract

Because of the special anatomical structure and physiological function of female reproductive tract, the evaluation of reproductive tract structure and function is also an important link in fertility evaluation, including vagina, cervix, uterus, fallopian tube and pelvic cavity.

1. Detection of vaginal microecology

Female reproductive tract flora is closely related to every step of ovulation, sperm transport, fertilized egg implantation, pregnancy and delivery. Reproductive tract infection of women of childbearing age affects their reproductive health, damages their reproductive function and increases the risk of infertility.

2. Detection of cervical lesions

Cervical diseases tend to be younger, which are closely related to fertility and pregnancy outcome. Regular gynecological physical examination, cervical liquid-based thin-layer cytology (TCT) and human papillomavirus (HPV) screening should be conducted to detect cervical diseases as soon as possible.

3. Detection of uterine abnormalities

Non-invasive ultrasound, such as hysteromyoma and endometrial polyp, is the most widely used examination method to evaluate the receptivity of uterus and endometrium, and to evaluate the shape, thickness, volume, peristalsis wave, uterine artery and hemodynamic parameters of endometrium. Hysteroscopy is the gold standard for the diagnosis of endometrial lesions, which can accurately identify cervical lesions, intrauterine lesions, abnormal endometrial morphology and abnormal tubal opening through endoscopy. Endometrial biopsy can also be performed. At present, there are cytokines, various receptors, endometrial receptivity chips and other detection methods to evaluate endometrial receptivity, and the research on endometrial receptivity is constantly expanding.

4. Tubal patency test

Including salpingostomy, hysterosalpingography/contrast-enhanced ultrasound and laparoscopic salpingostomy. At present, hysterosalpingography has become a research hotspot with its unique advantages (real-time dynamic, visualization and no radiation), and has gradually become the first choice for tubal patency examination. Liquid drainage has some shortcomings, such as invisibility, blindness and great difference. X-ray radiography, as a traditional method of tubal patency examination, mainly has the disadvantages of adverse reaction of contrast agent and radiation damage. Laparoscopic salpingostomy is the "gold standard", but it is not the first choice for the time being because of invasion, hospitalization, high cost, surgery and anesthesia.

The picture comes from the Internet.

5. Detection of pelvic factors

Pelvic diseases are closely related to female fertility, such as pelvic endometriosis, pelvic tuberculosis, pelvic adhesion, tubal diseases, hysteromyoma, ovarian tumors and pelvic inflammatory diseases. Laparoscopic surgery can find and diagnose abnormal pelvic conditions in time. For infertility caused by fallopian tube factors or uterine cavity factors, hysteroscopy combined with laparoscopy can treat pelvic cavity, fallopian tube and uterine cavity diseases accordingly, which has important clinical value for female fertility evaluation, diagnosis and treatment.

6. Female reproductive tract dysplasia

Abnormal development of female reproductive tract includes abnormal development of vagina, cervix, uterine body and fallopian tube, with or without abnormalities of ovary and urinary system. The combination of pelvic ultrasound and MRI examination is the best examination method for reproductive tract dysplasia.

Third, the general state assessment

In terms of systemic diseases, we should evaluate whether there are diseases that affect fertility or are not suitable for fertility, such as thyroid diseases, familial genetic diseases, blood system diseases, cardiopulmonary diseases and tumors.

1. Thyroid diseases

Abnormal thyroid function can lead to infertility and poor pregnancy outcome, so it is suggested that women with family planning should monitor thyroid function. Clinical hyperthyroidism can lead to abortion, premature delivery and thyroid crisis, and timely treatment can significantly reduce these risks; Infertile women with subclinical hypothyroidism should be treated with levothyroxine (LT4).

2. Hereditary diseases

According to the etiology, it can be divided into monogenic diseases, polygenic diseases, chromosomal diseases, mitochondrial genetic diseases and somatic genetic diseases, which have the characteristics of congenital, lifelong and familial. It is suggested that couples with rare diseases or couples who have given birth to rare diseases should have genetic testing and genetic counseling, reproductive risk assessment and guide reproductive decisions. The genetic diagnosis (PGD) before embryo implantation was provided after the pathogenic gene locus and genetic mode of the family were clarified.

3. Other general conditions

Nutritional status is a very important factor in regulating reproductive process, which is closely related to female reproductive function. For example, obesity and malnutrition have adverse effects on internal environment, egg quality and embryo development. In addition, mental state, living environment and systemic factors also need comprehensive consideration. Whether a woman’s whole system can withstand pregnancy is also the concern of fertility evaluation, including whether she is complicated with diabetes, hypertension, heart disease and tumor.

4. Who needs fertility assessment?

1. Couples who have been pregnant for more than 1 year without pregnancy;

2. People who have had many bad pregnancies in the past;

3. People who have had multiple abortions or ectopic pregnancy in the past;

4. Women of childbearing age with less menstrual flow, irregular menstrual cycle and dysmenorrhea;

5. Obese or thin people (BMI>24 or BMI<18.5);

6. White-collar workers who stay up late and work overtime for a long time;

7. People who use computers and mobile phones for a long time to work in a radiation environment;

8. People with smoking, drinking, drug addiction and other habits.

In a word, fertility assessment can help women understand their fertility potential and possible fertility problems. In fact, whether you have the desire to have children at present or not, regular fertility assessment can help you plan your birth plan reasonably, receive corresponding medical help in time, and don’t leave regrets for your life!

Central Meteorological Observatory: Heavy rain and strong convection warning are all in full swing, and the high temperature tolerance in Huanghuai and other places in North China is full.

  Cctv newsAccording to the Central Meteorological Observatory, yesterday, heavy rainfall mainly occurred in eastern Sichuan, northwestern and southwestern Shaanxi, central Shanxi, northeastern Shandong, central Guangxi, eastern Guangdong and other places, including Chengdu, Mianyang and Guangyuan in Sichuan, Hanzhong in Shaanxi, Baise in Guangxi and Shanwei in Guangdong. Thunderstorms or hailstorms occurred in southern Ningxia, north-central Shaanxi, western Shanxi, and central and eastern Shandong. It is estimated that there will be heavy rain or rainstorm in the southwestern Shaanxi, eastern Sichuan Basin, Jianghan, Jianghuai, northern Jiangnan, eastern Huanghuai, eastern North China, southern Liaoning and northern Heilongjiang on the 28th to 30th, with local heavy rain accompanied by obvious strong convective weather. The Central Meteorological Observatory continued to issue a blue warning for heavy rain and strong convective weather this morning.

  Today, there are heavy rainstorms in Liaodong Peninsula, eastern Beijing, northern Tianjin, northeastern Hebei, central and eastern Shandong, eastern Sichuan, southwestern Shaanxi, most of Chongqing and western Hubei, among which there is heavy rain (100-140 mm) in northern Chongqing, accompanied by short-term heavy rainfall (the maximum hourly rainfall is 30-50 mm, and the local area can exceed 60 mm). Parts of northeastern Inner Mongolia, southwestern Heilongjiang, central and western Jilin, southern Liaoning, southeastern Shaanxi, eastern Hebei, eastern Beijing, Tianjin, northern and eastern Shandong, northern Anhui, northern Jiangsu and other places will have 8-10 thunderstorms or hail weather, and the local wind can reach 11.

  The public should pay attention to the weather in time, prevent the adverse effects of heavy rainfall and local strong convective weather on traffic travel, and stay away from areas with high risk of meteorological disasters.

  In addition, it is expected that there will still be many hot weather in North China, Huanghuai and other places in the next two weeks, with the main high temperature periods from June 29 to July 2 and July 6-10. The daily maximum temperature in central Inner Mongolia, North China, Huanghuai and Fenwei Plain will be 35℃ ~ 39℃, and the local temperature can reach 41℃. High temperature weather is full of endurance, so the public should pay attention to temperature changes, reduce outdoor activities, take measures to prevent heatstroke and heat stroke.

Peng Yongtao: The service industry is running steadily and improving, and the role of modern service industry is highlighted.

  Since the beginning of this year, all localities and departments have resolutely implemented the decision-making arrangements of the CPC Central Committee and the State Council, made efforts to expand domestic demand and optimize the economic structure, and the service industry economy has achieved steady and rapid growth, and its contribution to economic growth has continued to increase, service demand has been accelerated, emerging service industries have grown rapidly, and market expectations have generally improved.

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  First, the service industry continues to improve, and the pulling effect is constantly increasing.

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  The service industry economy has accelerated its recovery. Preliminary accounting, in the first three quarters, the added value of service industry530651100 million yuan, a year-on-year increase4.7%. The proportion of added value of service industry in GDP is55.9%, up from the same period of last year.0.3Percentage points, the contribution rate to national economic growth is53.9%, stimulate GDP growth.2.6Percentage points. Among them, in the third quarter, the added value of service industry181005100 million yuan, a year-on-year increase4.8%, faster than the second quarter.0.6Percentage points.9In September, the service industry production index increased year-on-year.5.1%, than8Speed up the month0.5Percentage points.

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  The production and operation of enterprises continued to improve.one8In September, the operating income of service enterprises above designated size increased year on year.7.7%, thanonesevenMonthly increase0.3Percentage points, of which leasing and business services industries maintained rapid growth;35There are three industry categories.33Each industry is profitable, and the industry is profitable.94.3%, thanonesevenMonthly increase2.9Percentage points.

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  Trade in services has grown rapidly.one8Total import and export of services in June48865.6100 million yuan, a year-on-year increase14.3%The import and export of travel services increased year-on-year.45.0%, the largest field of service trade.one8In September, the execution amount of service outsourcing undertaken by Chinese enterprises increased year on year.14.4%Among them, information technology research and development services, design services and maintenance services grew rapidly, and the implementation amount increased respectively year-on-year22.2%22.1%15.8%.

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  Second, the modern service industry is growing well, and the pace of transformation and upgrading is accelerating.

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  The modern service industry is booming. In the first three quarters, the added value of information transmission software and information technology services, leasing and business services, and financial services increased respectively year-on-year.11.3%10.1%5.2%, to promote the growth of added value of service industry.2.4Percentage points, to provide strong support for accelerating the formation of new quality productivity. In the third quarter, the added value of information transmission software and information technology services, leasing and business services, and financial services increased respectively year-on-year.10.0%10.8%6.2%, to promote the growth of added value of service industry.2.4Percentage points.9In September, the production indexes of information transmission software and information technology services, leasing and business services, and financial industry increased respectively year-on-year.11.4%9.7%6.5%.

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  Endogenous kinetic energy has developed and grown. In terms of investment, in the first three quarters, the investment in fixed assets of high-tech service industry increased year-on-year.11.4%, accounting for the proportion of fixed assets investment in all service industries4.8%. Among them, fixed assets investment in e-commerce services, scientific and technological achievements transformation services, research and development and design services increased respectively year-on-year.14.8%14.8%13.7%. In terms of consumption, retail sales of services increased year-on-year in the first three quarters.6.7%, higher than the growth rate of retail sales in the same period.3.7Percentage points; The per capita service consumption expenditure of national residents increased year-on-year7.6%, accounting for the proportion of per capita consumption expenditure of residents is47.0%, higher than the first half of the year.1.4Percentage points. From the perspective of industry,one8In January, the operating income of high-tech service enterprises and strategic emerging service enterprises above designated size increased respectively year-on-year.9.5%7.8%The growth rate is higher than that of all listed service enterprises.1.80.1Percentage points; The operating income of enterprises above designated size in science and technology service industry, science popularization and application service industry increased respectively year-on-year.8.3%11.6%.

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  Integration, development and acceleration. Digital technology innovates consumption scenarios, and its integration with the real economy continues to deepen, promoting market sales growth. In the first three quarters, the online retail sales of physical goods increased year on year.7.9%, accounting for the proportion of total retail sales of consumer goods25.7%. Industrial Internet promotes the level of industrial intelligence and digitalization.one8In January, the operating income of enterprises with integrated circuit design and Internet production service platforms above designated size increased respectively year-on-year.30.0%18.3%. Cultural tourism is deeply integrated, and large-scale performances are deeply linked with scenic resources around the country to stimulate new potential of tourism consumption. In the first three quarters, the e-commerce transaction volume of tourism and entertainment services increased year-on-year.15.3%.one8In January, the operating income of travel agencies above designated size and related services and leisure and sightseeing enterprises increased respectively year-on-year.28.5%9.6%.

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  Third, positive factors are increasing, and market expectations continue to improve.

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  Recently, with a series of policy "combination boxing" efforts, confidence in the capital market and real estate market has been enhanced.9月份,沪深股市股票成交量和股票成交额分别由8月份同比下降15.3%31.0%转为同比增长32.7%4.9%9月份,房地产业生产指数同比下降2.2%,降幅连续5个月收窄。

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  9月份,服务业业务活动预期指数为54.6%,其中零售、铁路运输、航空运输、邮政、电信广播电视及卫星传输服务、货币金融服务等行业业务活动预期指数位于55%以上较高景气区间,企业对近期行业发展较为乐观。

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  总体来看,前三季度服务业经济运行稳中向好,随着各项已有政策和一揽子增量政策效应不断显现,经济发展的活力和动力将进一步释放,市场信心有望继续增强,服务业经济平稳运行的基础将不断夯实。下阶段,要狠抓政策落地见效,积极培育服务业新动能,加快构建优质高效的服务业新体系,推动服务业发展的质量和效率继续提升。

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  (作者系国家统计局服务业调查中心主任)

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  (原文链接:http://www.ce.cn/xwzx/gnsz/gdxw/202410/18/t20241018_39173114.shtml

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Is online celebrity Scenic Area "Wild"? Be wary of "fairyland" becoming dangerous!

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In recent years, some undeveloped "wild" scenic spots have become punching places in online celebrity on social platforms. There are hidden safety risks behind the fiery "adventure". The safety management protection network of undeveloped scenic spots needs to be woven by many subjects such as government, platform, travel agency and tourists.

 

On both sides of the crystal clear river, colorful tents and awnings are set up, and tourists play in the river. However, in an instant, the flood came in with sediment, and the tourists even had no time to put away their camping equipment and fled to the shore, but some people were still trapped in the middle of the river, in a dilemma &hellip; &hellip;

This is the scene of a sudden flash flood in Longcaogou, Longmenshan Town, Pengzhou City, Sichuan Province on August 13th. According to the report of Pengzhou Emergency Management Bureau, 7 people were killed and 8 people were slightly injured in the disaster. In fact, Longcaogou, which was favored by tourists before the disaster, is an undeveloped "wild" scenic spot.

The mountain torrents in Pengzhou once again sounded the alarm. In recent years, some undeveloped scenic spots have become "original ecological scenic spots" and "niche punching places" on social platforms, attracting many tourists, and "adventure" tourism has even become a popular game, but the hidden security risks behind it cannot be underestimated.

There is a hidden crisis behind the fiery "exploration"

Half a month after the flash flood in Pengzhou, when the reporter searched for "Longcaogou" on the social platform again, "fear nature and cherish life" became a frequent word.

In recent years, outdoor tourism, such as exploration and camping, has become popular. Many "wild" attractions like Longcaogou have become online celebrity attractions on social platforms, such as the abandoned mine cave in Jiande, Hangzhou, Zhejiang, the "sheepskin cave" in Guiyang, Guizhou, and the Shilaoren cave in Qingdao, Shandong.

Yin Jie, a professor at the Institute of Tourism Safety of Huaqiao University, analyzed that from the perspective of demand, tourists’ favorite travel mode has changed from sightseeing to experience tourism. Camping, outdoor exploration and other activities have high experience attributes, and affected by the epidemic situation in COVID-19, tourists’ yearning for natural space is becoming stronger. With the double blessing of "experience" and "being close to nature", tourism modes such as outdoor adventure continue to be hot.

However, there are hidden security risks behind the fiery "adventure", and tourists are in distress frequently. On June 29, two tourists fell off the cliff while climbing the "sheepskin cave", causing leg fractures and head injuries; On August 20th, a woman accidentally fell into the water and died while playing paddle board in Xiangtang Reservoir in Nanjing &hellip; &hellip;

Yin Jie said that tourists who visit undeveloped scenic spots without authorization may not only face the risks of natural disasters such as floods, mudslides, landslides and landslides, but also have accidents such as falls, sprains, falls and disappearances. Zhang Yuxin, a member of the Kunming Blue Sky Emergency Coordination Center in Yunnan Province, said that taking mine exploration as an example, the internal structure of the cave is complex, and there is no communication signal. After entering, it is easy to get lost, and there may be air scarcity or landslides. Once tourists are trapped, it is very difficult to search and rescue.

Who’s to blame for swimming in "Wonderland" but encountering danger?

Areas that are not suitable for travel have become popular tourist attractions, and tourists’ expectations for visiting "fairyland" have evolved into a tragedy of encountering danger. Who will be responsible for this?

At one time, Longcaogou was dubbed as "a good place to spend the summer" and "a little-known secret place to play with water" on social platforms, but these recommendations usually made no mention of the fact that Longcaogou was prone to natural disasters such as mudslides and flash floods during the flood season, and even undertook local flood discharge tasks.

"The product development, service management, system norms and other aspects of this kind of scenic spot are imperfect and unsystematic." Yin Jie said that becoming a punch-in point in online celebrity depends largely on the "online celebrity spillover" effect and the "filter beautification" effect, that is, the fan effect of the recommender and the beauty function of the lens.

Wang Xudong, a lawyer of Beijing Dongwei Law Firm, said that the "wild" scenic spot can not be turned into a punching point in online celebrity without the sharing of some bloggers on social platforms and the promotion of the platform based on algorithms. In the face of the massive information released by users, it may be harsh to ask the platform to actively delete each recommended scenic spot after risk assessment. "However, if a user complains or reports the danger of the site, the platform has the obligation to confirm and review it in time, and cannot let itself go." Wang Xudong said.

Yin Jie believes that tourists who travel after watching recommended videos have a safety accident, which belongs to "multiple causes and one effect". It is impossible to judge that the safety accident must be caused by information publishers or social platforms, especially in the case of undeveloped scenic spots and no complete supporting facilities.

In the travel itinerary provided by many tourists who witnessed the Pengzhou flood, the reporter saw that on the same day, they participated in the trip of "Cool Walking, Zhongba Forest+Longcaogou" of a travel agency. In this regard, Wang Xudong analyzed that travel agencies have the obligation to ensure the safety of tourists, and should fully inform the common risks in tourist routes and take effective protective measures. If the travel agency fails to fulfill the relevant obligations, causing personal injury and property loss to tourists, it should bear the corresponding liability for compensation.

The popularity of "wild" scenic spots has also revealed that some tourists have poor safety awareness. "As a person with full capacity for civil conduct, tourists should have the ability of independent judgment, improve their safety awareness and be more awed by nature. If tourists are still willful after receiving sufficient risk warnings, they should be responsible for it. " Wang Xudong said.

Weave the safety management protection net together.

The reporter found on the social platform that although Longcaogou is no longer recommended as a scenic spot, there are still many other "wild" scenic spots that are continuously shared and recommended, covering ruins, caves, jungles, canyons and other places. In the context of global tourism, the safety management protection network of "wild" scenic spots needs to be woven together by the government, platforms, travel agencies and tourists.

"Most of these scenic spots are located in remote areas. In case of danger, rescue may be difficult. It is extremely necessary for relevant departments to take effective preventive measures in advance." Wang Xudong said.

Yin Jie also said that government departments should do a good job in comprehensive management, risk monitoring and early warning of scenic spots and non-scenic spots, conduct a comprehensive investigation of potential risks in tourist reception places, strengthen risk information monitoring in conjunction with hydrology, meteorology, transportation, geology, emergency management and other departments, release early warning information in time, implement early hidden danger control measures, and build an emergency response system.

"Sharing risks and difficult adventure routes without explanation will often make tourists ignore potential risks and increase the difficulty of on-site dissuasion." Yin Jie said that for social platforms, we should focus on understanding and mastering the potential risks of tourist reception places, and add risk tips and safety knowledge popularization to content recommendation. When choosing routes and destinations, travel agencies need to comprehensively consider potential risks, surrounding emergency rescue facilities, and territorial safety rescue capabilities, and at the same time clearly inform tourists of possible risks and countermeasures.

The safety awareness of tourists is related to their own safety. Yin Jie believes that tourists should establish a "global" risk awareness, that is, they should recognize that risks may occur at any moment, strengthen self-protection, obtain extensive risk information before visiting, improve their travel emergency skills, reasonably choose tour routes, and abide by tour norms.

Can’t beat Sam and Costco? Yonghui Warehouse Supermarket closed its store one year after its opening, and customers spit out too many miscellaneous brands.

  In addition to the collapse of supermarkets, Yonghui’s super species and mini stores have also shrunk rapidly. The warehouse supermarket, which began to expand vigorously last year, faced the dilemma of closing its stores for the first time.

  One year after exploring the "warehouse store" model, Yonghui Supermarket (SH:601933) ushered in the closing of the first warehouse supermarket.

  A few days ago, Yonghui Supermarket Shijiazhuang White Plaza Store announced the closing of the store for clearance. According to the signs in the store, the clearance promotion period lasted from July 29th to August 7th. It is reported that the store opened in November 2014, and in July last year, it became one of the experimental stores where Yonghui transformed hypermarkets into storage supermarkets.

  In recent years, domestic hypermarkets are on the ebb tide, and Wal-Mart, Carrefour and Yonghui have frequently closed their stores. In addition to folding the hypermarket, Yonghui’s super species and mini stores have also shrunk rapidly. The warehouse supermarket that began to expand aggressively last year faced the dilemma of closing its stores for the first time.

  Under the preferential efforts of 30% off clearance, the store triggered a rush to grab goods. "When I went, there were a sea of people, and I came out without buying anything." Local resident Xiao Chen (pseudonym) said that as of August 2, many shelves in the supermarket were empty.

  In fact, driven by Costco and Sam, the founders of warehouse member stores, domestic supermarkets have entered the market one after another, running out of two forms: warehouse member stores and warehouse supermarkets. The former can only enter by paying for membership, while the latter has no restrictions. In terms of scale, Yonghui is currently the head player of the free storage supermarket. Since the trial in May 2021, a total of 53 stores have been opened by the end of that year.

  However, Time Finance found that domestic players, such as Box Horse and Yonghui, seem to be still in a simple imitation stage, and their fist products, such as roast chicken, Swiss rolls and cheese rolls, are very similar to those in Sam.

  I opened 53 storage supermarkets in 7 months, but I was told that they were all miscellaneous brands.

  In Shijiazhuang market, well-known supermarket chains such as Beijing Hualian, Century Lianhua, Wankelong, Shenzhen Renrenle, Beijing Huapu are as busy as they are when they come, and as embarrassed as they leave.

  Among them, Yonghui’s White business district is the most competitive, and local enterprises such as Baolongcang, Beijing Huapu and Yichu Lotus have settled here successively, and then left angrily. Now with the exit of Yonghui Warehouse Supermarket, northland supermarket, the local strongman, has become the final winner.

  In 2011, Yonghui Supermarket entered the Hebei market, and expanded 9 stores within 3 years, becoming a small scale. In 2014, it opened its doors on the first floor of White Square to welcome guests, with a leased area of 13,115 square meters. The store was separated from northland supermarket by a street, and they had a hand-to-hand fight in the following eight years. In 2022, northland supermarket celebrated its 15th anniversary, but Yonghui ended in failure.

  A supplier of Yonghui Supermarket told Time Finance that when Yonghui first entered the Shijiazhuang market, a local supermarket had an operation to let the supplier choose one.

  According to public information, northland supermarket belongs to Shijiazhuang Beiguobai Group Co., Ltd., with a state-owned background, and its commercial map involves shopping centers, department stores, cultural tourism and entertainment, community commercial complexes, catering services, supermarkets, warehousing and transportation, jewelry and other formats. Company official website shows that it has 37 supermarkets in Shijiazhuang, covering a wide range.

  In addition, due to the great influence of northland supermarket and its parent company in Shijiazhuang, supermarket shopping cards are still the choice for many enterprises to distribute employee benefits. There is a local saying that half of the people in Shijiazhuang have shopping cards from northland supermarket.

  Time Finance learned that after Yonghui upgraded its warehouse supermarket in July last year, it made a compromise in product selection in order to make up for the profit gap caused by the decrease in gross profit. On the one hand, there are more miscellaneous brands in supermarkets, such as 1828 herbal tea toothpaste, which is being cleared and sold in 5 yuan. "I have never heard of this brand, and I feel that what northland supermarket sells is a brand, so Yonghui Supermarket has few brands, so I go less," said resident Jingjing (a pseudonym).

  On the other hand, storage supermarkets are characterized by expanding the number of stores, streamlining the number of goods (SKU) and large packaging. Although large-scale sales are conducive to increasing the unit price of customers and attracting family customers, streamlining SKU puts forward higher requirements for the supply chain and product selection ability, and consumers have fewer choices. Therefore, when the quality of the goods can’t win, the decrease of the available categories will lead to the loss of consumers.

  Local residents have a deep understanding of this. Xiao Ke (pseudonym) told Time Finance: "It may be because there are too few kinds of goods, and the things provided by the North are really complete." However, according to her, she went to Yonghui more often than in the north, "because Yonghui has fewer people and provides pet dog cages, which is very friendly to consumers with pets."

  In May 2021, Yonghui announced to test the water storage supermarket. In July, it took the lead in closing and upgrading the store in Dongsheng Square, Shijiazhuang. According to the annual report data, by the end of 2021, Yonghui had opened 53 storage supermarket stores. However, while expanding its stores in a big way, Yonghui Supermarket harvested its first annual report of revenue decline since listing. In 2021, its operating income decreased by 3.8% year-on-year, and the net profit attributable to shareholders of the parent company was 3.93 billion yuan, a decrease of 5.72 billion yuan compared with the same period of last year.

  Lack of explosive ability, staying in the imitation stage.

  In August 2019, Costco, the head enterprise of warehousing member stores, entered China and landed its first store in Shanghai. On the opening day, the roads around the store were congested and there was a large passenger flow in the store, which led to the suspension of business that afternoon.

  Sam entered China in 1996. According to the data released by Wal-Mart China, by the end of November 2021, the number of Sam member stores in China had reached 36, the number of members exceeded 4 million, and the membership fee income was 1.04 billion yuan. Wen Ande, President of Sam Member Store and Deputy CEO of Wal-Mart China, said that by the end of 2022, the number of member stores in Sam will reach 40-45.

  Foreign players have a strong momentum, and domestic retailers are super aware that the spring of warehousing membership is coming. Since then, Box Horse, Yonghui, Metro China, etc. have entered the market one after another, and launched two forms, namely, a charging warehouse member store and a non-charging warehouse supermarket, which are regarded as the company’s second growth curve. In order to become the winner of the new track, all enterprises regard store expansion as the first step to seize the market.

  After Metro China was acquired by Wumart, in May, 2020, it began to launch a paid membership program in 13 Metro stores, namely, PLUS membership, with a price of 199 yuan/year. Wumart’s prospectus shows that as of December 31, 2020, the number of PLUS members has increased to 1.48 million, of which 11 metro stores account for 48% of the total customers, and the order volume accounts for 67% of the total orders, which indicates that the membership plan will be gradually extended to other metro stores in the Mainland. On November 27th last year, Metro opened 16 member stores in 8 cities including Beijing and Nanjing.

  In May, 2021, Yonghui tried out the warehouse member store model. According to the financial report, by the end of the year, 53 stores had been opened, and the same-store sales increased by 32.9%. In October, Carrefour’s first member store in China was established in Shanghai. According to the plan, 100 hypermarkets will be upgraded and transformed into member stores in the next three years. Box horse, Beijing Hualian and others also entered the game.

  However, the track of the warehouse member store, which was still bustling in 2021, became quiet in 2022. According to the statistics of public information in Time Finance, so far this year, Metro China and Fudi have added one member store, Yonghui has added two, Carrefour China, northland supermarket, Jiajiayue and Beijing Hualian have added zero, which is in contrast with the rapid expansion of stores in 2021.

  On the other hand, foreign warehouse players are still making steady progress. Costco currently has three stores in China, including Shanghai, Suzhou and Shenzhen, but it has successively acquired land in cities such as Hangzhou, Shanghai and Nanjing to prepare for the opening of new stores. In July, Sam issued a recruitment notice at Wal-Mart, announcing that seven stores will open in Shanghai, Chongqing, Nanning, Changsha, Wuxi and Beijing in the second half of the year.

  A few days ago, Time Finance visited Tianhe Store in Guangzhou, Sam. Although it was a working day, the store was crowded with people. A family of three is almost a standard for customers. Children sit in shopping carts with all kinds of big items piled up behind them. Crayfish, milk, cold-soaked cold dishes and other tasting tables all need to line up. On that day, the croissants in the store were on sale, and almost every shopping cart contained one or two boxes.

  The staff said that this stream of people is not too much, and there are too many customers to walk on weekends. In the store, several elderly customers also told Time Finance that they had five old sisters in total, and they would come together to replenish the goods on weekdays from time to time. "The goods are of good quality and the prices are acceptable."

  However, domestic storage supermarkets are more in the imitation stage. Hou Yi, CEO of Box Horse, once said that Box Horse X member stores have borrowed from Costco in many ways. Time Finance noticed that the roast chicken, Swiss roll, potato, croissant, cheese beef roll and lime juice displayed in Boxma and Yonghui stores are all out-of-the-box products in Sam, and their prices are generally lower than those in Sam.

  It is worth noting that warehouse member stores are not superficially large-package, low-SKU, nor are they the same explosive products. The core logic behind them is the real competitiveness, such as inventory turnover speed, supply chain, product selection and customer positioning. For domestic warehouse supermarket players, it is better to sort out the logic behind the warehouse supermarket before expanding, which may be more conducive to long-term development.

Cadillac XT6 in Yancheng is on sale! The latest offer is 349,900 yuan, and the discount waits for no one.

[car home Yancheng Preferential Promotion Channel] Recently, a large-scale preferential promotion activity was ushered in in Yancheng area, and the maximum preferential amount reached 100,000 yuan. At present, the minimum starting price of this luxury SUV has dropped to 349,900 yuan, which has brought more car purchase options to consumers. If you are interested in Cadillac XT6, you may wish to click "Check the car price" in the quotation form and strive for higher discount!

盐城地区凯迪拉克XT6正在优惠!最新报价34.99万,优惠不等人

Cadillac XT6 adopts a unique front face design, and the front grille is decorated with chrome trim. The overall shape presents a strong sense of movement. The body lines are tough and smooth, creating a sense of luxury and strength. The overall style is luxurious and atmospheric, showing the unique charm of Cadillac brand.

盐城地区凯迪拉克XT6正在优惠!最新报价34.99万,优惠不等人

Cadillac XT6 has a spacious body size, with the length, width and height of 5056*1964*1780mm respectively and the wheelbase of 2863mm, which provides ample space for the passengers in the car. The side lines of the car are smooth and elegant, showing a sense of luxury and sports style. The equipped 20-inch rim adopts a unique design, and with 235/55 R20 tires, the overall visual effect and driving stability of the vehicle are improved.

盐城地区凯迪拉克XT6正在优惠!最新报价34.99万,优惠不等人

The interior of Cadillac XT6 adopts a luxurious and technological design style. The steering wheel is made of leather and supports electric up-and-down and front-and-rear adjustment, which brings a more comfortable driving experience. The center console is equipped with a 10-inch touch screen, which supports voice recognition control system and can control multimedia system, navigation, telephone and air conditioning. Both the front seat and the co-pilot seat are made of leather and have heating and ventilation functions. The main driver’s seat is also equipped with electric seat memory function. The second row of seats supports front and rear and backrest adjustment, while the rear seats can be laid down in proportion to increase luggage space. In addition, the car also provides a wealth of multimedia/charging interfaces, including two USB interfaces in the front row and four Type-C interfaces in the back row to meet the charging needs of different passengers.

盐城地区凯迪拉克XT6正在优惠!最新报价34.99万,优惠不等人

Cadillac XT6 is equipped with a 2.0T turbocharged engine, with a maximum power of 174 kW (237 HP) and a peak torque of 350 Nm, showing strong power performance. Matching it is a 9-speed automatic manual transmission, which enables the vehicle to maintain smooth and efficient performance under various driving conditions.

Our purchase experience fully embodies the comprehensive advantages of Cadillac XT6, which can meet the needs from business use to family travel. Although at first @Drwan007 hesitated about the choice of models, he and his family were full of praise for this large SUV after personally experiencing it. As he said, "With this cart, it’s really convenient to set up a tent, see the scenery and relax. It’s never been so beautiful for a long time." Cadillac XT6 can not only meet the daily travel needs, but also bring more fun and convenience to the family.

Ningbo area eπ 008 is being discounted, and the discount 28,000! Quantity is limited

[Autohome Ningbo Discount Promotion Channel] Recently, a large number of promotions have been ushered in in the Ningbo market, with the maximum discount amount reaching 28,000 yuan. Buy eπ 008 now, and the minimum starting price is only 188,600 yuan. If you are interested in eπ 008, you may wish to click the "Check Car Price" link in the quotation form to get a higher discount.

宁波地区eπ008正在优惠,优惠2.8万!数量有限

eπ008的外观设计采用了一种极具未来感的风格,前脸采用了封闭式进气格栅,配合犀利的LED大灯,展现出独特的科技感。车身线条流畅,整体造型紧凑且动感十足,勾勒出充满力量感的车身轮廓。这样的设计不仅满足了现代消费者对美学的追求,还充分展示了eπ008的独特个性和卓越品质。

eπ008的车身尺寸为5002mm*1972mm*1732mm,轴距达到了3025mm。车身线条流畅,展现出独特的美学设计。前后轮距均为1650mm,保证了车辆的稳定性和操控性。轮胎规格为265/45 R21,搭配精致的轮圈设计,进一步提升了车辆的运动感和时尚感。

宁波地区eπ008正在优惠,优惠2.8万!数量有限

eπ008的内饰设计以简洁优雅为主,中控台配备了一块15.6英寸的高清触控屏幕,支持多媒体系统、导航、电话及空调的语音识别控制,带来智能化的驾乘体验。方向盘采用皮质材质,支持手动上下和前后调节,手感舒适。前排配备手机无线充电功能,方便快捷。座椅采用仿皮材质,主副驾驶座椅具备加热和通风功能,主驾驶座椅还配备了头枕扬声器。此外,前排座椅、副驾驶座椅和后排座椅均具备电动记忆功能,提升乘坐舒适度。第二排座椅支持前后调节、靠背调节和腿托调节,放倒后可形成平整的后备箱空间。

宁波地区eπ008正在优惠,优惠2.8万!数量有限

eπ008搭载了一台高效强劲的电动机,其最大功率为200千瓦,峰值扭矩达到340牛·米,为车辆提供了卓越的动力输出和加速性能。

汽车之家车主对eπ008的外形给予了高度评价,他提到:“外形很大气!前脸很帅!颜值高!开出去回头率很高!车标也简洁!”这样的设计确实让人眼前一亮,无论是行驶在繁忙的城市街道还是宁静的乡间小路,eπ008都能成为路上的一道亮丽风景线。

2022 Mercedes-Benz GLE450 riders evaluate 750,000 price is very fragrant

  2022 Mercedes-Benz GLE450 (Configuration | Inquiry) Detailed configuration: Mercedes-Benz GLE450 22 7-seat, luxury bag, sports bag, intelligent driving bag, metallic paint, 7-seat, luxury bag, sports bag, driver assistance bag, third-row seat bag, calfskin, pedal, front windshield heating, black inner top, luxury bag: Voice of Berlin, foot-sensitive tail, keyless entry, one-button start, rapid heating of front seats, heating of front armrests and upper door panels, second-row seat heating, ring shadow, sports bag: AMG sports surround, 20-inch AMG5 spoke hub, driver assistance bag: intelligent pilot range function (lightning test), active steering assistance system, avoidance steering assistance system, active braking assistance, cross traffic function, active emergency braking assistance Active blind spot assist, active merge assist, preventive safety system enhancement, active driving assistance system, active lane keeping assist, third row seat package: third row seat, electrically adjustable second row seat, third row dual USB interface, single choice: calfskin, pedal, front windshield heating, black inner top.

  It is very important for the Mercedes-Benz GLE450 to adhere to the classic feelings, and it is also very important to make a drastic change. Many people around me have chosen other models because of the old GLE’s old and lackluster interior, so this replacement interior change is imminent. Compared with the old model in the new generation GLE, the change can be described as very thorough. The addition of dual screens and the trend of central four air conditioners has brought more technological atmosphere in the car in addition to the usual luxury. The wrapping center console strikes a good balance between sports and luxury. The center console is wrapped in high-end soft materials, and there is also a stitching process and a large area of wood grain veneer to embellish.

  The 22 Mercedes-Benz GLE450 models are equipped with high-end leather-wrapped seats, providing unquestionable comfort and softness. The second-row space is also very abundant, with a large leg gap. The second-row independent electric seat adjustment makes it easy for the occupant to operate without making the occupant feel crowded and tired. It is the first model for family cars.

  Solemnly promise: All models purchased in this company are imported with original equipment, without private modification, and can provide regular goods import certificates, vehicle consistency certificates, imported motor vehicle inspection sheets, and regular invoices issued by the state-recognized customs to ensure normal settlement in all regions of the country. At the same time, all vehicles of our company can enjoy the national mandatory three-year 100,000-kilometer quality assurance, so that you can buy comfortably and use with confidence.

  At the same price, there are more imported cars than 4S shop cars.  

  2 Equivalent configuration, imported cars are cheaper than 4S shops.

  The quality of imported cars is better than that of 4S shops. 

  4 All models are bare car prices, and our company does not require any other expenses (insurance, decoration).  

  5 Parallel imported mortgage car purchases can be done nationwide, details of the ITU. 

  6 Signing a contract with our company has legal benefits, the procedures are normal, and the car can be picked up at any time. Continue normally and pick up the car at any time.

  Car purchase triple guarantee   

  The first guarantee: the original regular commodity car, to ensure that the new car is not a repair car, and the modified car.   

  The second guarantee: to ensure the quality, the manufacturer has done professional testing for each car before leaving the factory.   

  The third guarantee: the procedures on the day of purchase are taken away with the car (close the ticket, commodity inspection, consistency certificate, electronic information QR code)

  Dealer Name: Tianjin Tengyuande Automotive Trading Co., Ltd.

  Dealer address: Hall B, International Automobile City, Tianjin Port Free Trade Zone

  Dealer Tel: 17726039870 (with WeChat) Manager Liu

  Disclaimer: The above car purchase discount information is provided by the comprehensive dealer of this website. Due to market factors, the price fluctuates greatly, and it is only for the reference of car purchase. Its authenticity, accuracy and legality are the responsibility of the dealer. This website does not provide any guarantee and does not assume any legal responsibility.

Not affected by the financial tsunami, Soda Green Guo Fucheng’s Guangzhou concert is hot


  The "financial tsunami" did not seem to affect the enthusiasm of Guangzhou’s neighbors for the carnival at the end of the year. In the next month, the concerts in Guangzhou gathered, and the tickets were sold more and more expensive, and even a rare thousand yuan ticket appeared. The reporter received news from various performers yesterday that whether it was the king Guo Fucheng or the "niche" soda green, the tickets were selling crazy, and there was even a hot scene that the tickets were not officially sold out and had been booked out.


  Guo Fucheng


  The box office on the first day exceeded one million


  On January 3, 2009, Guo Fucheng will bring his Asia-renowned "Dancing Forest True Concert" and the Guinness World Record 450-degree giant rotating stage to the Tianhe Stadium in Guangzhou. This is also his return to perform in Yangcheng after a seven-year absence from the Guangzhou stage. As soon as the news broke, fans who like him were excited. The organizers were originally scheduled to officially issue tickets yesterday, but due to the large number of fans booking tickets in advance, some price tickets are actually "unavailable".


  According to the organizers’ statistics, within 24 hours of the "Dancing Forest True Story Concert" going on sale, ticket sales have exceeded one million.


  The organizers introduced that in order to give back to Guangzhou fans and coincide with the two major festivals of Christmas and New Year, they have specially prepared a limited edition New Year’s card for Guo Fucheng. All fans who purchase tickets at Guo Fucheng’s designated ticket outlets in Guangzhou will receive a free exquisite card as a New Year’s gift from Guo Fucheng to Guangzhou fans.


  The organizers also revealed that the concert also specially planned to build an extension platform dozens of meters long on the stage, which will be the first time the extension platform will be used in a concert in Guangzhou. At that time, Guo Fucheng will stand on the extension platform to get up close and personal with fans, and will also deliver mysterious gifts to the audience on the spot.


  Soda Green


  Tickets are selling out fast


  If Guo Fucheng’s ticket sales are particularly good because he has a strong mass base in Guangzhou, it is quite surprising that the rather "niche" soda green tickets can also be sold out.


  Soda Green, which has always been known as a "niche" band, started singing at the Taipei Arena at the end of last year, and held solo and commercial performances in Hong Kong, Beijing, Shanghai, Tokyo, Chengdu and other places within a year, so that fans in each place can truly feel the charm of Soda Green’s live music interpretation, and at the same time, it has also won commercial success.


  This Christmas Eve, Soda Green will hold its last solo concert of 2008 in Guangzhou, with the theme of "Soda Green Sings with You on Christmas Eve". Although there was no much hype, the tickets sold out quickly after being issued. At the strong request of many fans, the organizers temporarily decided to adjust the performance venue, replacing the Zhongshan Memorial Hall, which was originally scheduled to accommodate 3,000 spectators, with the Guangzhou Stadium, which can accommodate 8,000 spectators. However, even if it is changed to the stadium, the low-priced tickets have been sold out.


  In addition, in order to give back the fans’ support for Soda Green, the performers have reserved a small number of free tickets, and specially planned the Soda Green "Sing with me on Christmas" ticket-grabbing activity on December 24. Once launched, it attracted millions of fans to leave messages online to grab tickets, and the popularity was bursting. This is another successful case of Chen Qizhen expanding the scale of her performance due to the hot box office after her solo performance in Beijing not long ago. In this year’s performance market, the explosive power of so-called independent and niche singers such as Cai Jianya, Chen Qizhen, and Zhang Zhenyue, who will be singing in Beijing, has also impressed everyone with nearly 10% of the box office sales.


  Soda Green has been out for three years and has released 4 albums and 5 EPs, which are deeply loved and sought after. In the first large-scale ticketed concert held at Taipei Arena in November last year, Qingfeng sang more than 40 songs in a row, returned 8 times, and performed for 5 hours. Soda Green expressed the hope that this Guangzhou concert can continue the performance myth of Taipei Arena and bring more unparalleled musical experience to the live audience.


  At the same time, Cai Yilin, Luo Zhixiang, and Zhou Huajian, who will be singing in Guangzhou at the end of the year, are also enthusiastically sought after, and the box office good news has come again and again. Everyone is like a competition to see who will run to the "limit" first. Reporter He Yajia

Editor in charge: Sun Jie

Meizu (meizu) mobile phone MEIZU 21 5G mobile phone 12GB + 256GB smart purple, how much is the Snapdragon 8Gen3?

In terms of appearance design, it adopts the design of straight plate and arc edge frame, and provides four color schemes of Ruiyi Blue, Unbounded Black, Meizu White and Smart Purple in the color scheme. The whole machine is 7.9mm thick and weighs 198g. In terms of screen, it is equipped with a 6.55-inch 120Hz AMOLED screen, ultra-narrow four equilateral, the frame is only 1.74mm, supports DCI-P3 wide color gamut, 1800nit peak brightness, 1500Hz instantaneous sampling rate and 1920Hz PWM high frequency dimming, and passes SGS low blue light eye protection and mLight 10,000-level dimming. In terms of performance, it is equipped with the third-generation Snapdragon 8 processor and adopts TSMC 4nm process. In terms of storage, it provides 8GB + 256GB, 12GB + 256GB, 12GB + 512GB optional. In terms of heat dissipation, it adopts a 37345mm2 super-large area heat dissipation system and a 4045mm2VC liquid-cooled heat dissipation plate, which dissipates heat faster and more efficiently. The exclusive "Ice World" cooling technology is blessed, and the game experience is further improved. In terms of battery life, it is equipped with a 4800mAh large battery and supports 80W fast charging. In terms of imaging, the front Samsung 32MP lens, the rear 200MP main camera (supports OIS optical anti-shake) + 12MP ultra-wide-angle lens + 5MP depth of field lens. In other aspects, it brings a richer Aicy smart ring to provide more interactivity. Supports ultrasonic fingerprint recognition and supports wet hand unlocking. Equipped with the sixth generation master-level "dual" and ultra-linear speakers, it is the first mobile phone to pass the QQ music "premium product certification" panoramic sound playback. Equipped with a horizontal linear motor, the vibration feedback is more obvious. Adopting a new antenna architecture, the WiFi signal is greatly improved; running the Flyme 10.5 system, the use is more stable and smooth, and the interaction is better with intelligence.