Fertility assessment helps women better understand their fertility potential.

Authors: Deputy Chief Physician Zhu Xiaodan, Department of Obstetrics and Gynecology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine.

At present, the global fertility problems are increasing day by day, and the overall fertility of women is on the decline. Women are facing various pressures in modern society, including occupational pressure, family pressure, social expectations, and the unhealthy lifestyle that follows, which makes the fertility of contemporary women decline more and more "younger". At present, the incidence of infertility is as high as 10%~18%. In 2023, the birth rate in China was as low as 6.4‰.

National birth rate

In the reproductive endocrinology clinic, patients often ask: How is my fertility? Can you still be born? Faced with such a question, today, let’s talk about this topic.

As we all know, to complete a successful pregnancy, women need the cooperation of the whole reproductive system and all organs of the whole body. Therefore, the evaluation of female fertility is divided into three parts: the first part is the evaluation of ovarian reserve function, the second part is the evaluation of the structure and function of uterus and fallopian tube, and the third part is the evaluation of general state.

First, the ovarian reserve function

The ovarian reserve function of women refers to the quantity and quality of eggs, that is, the "inventory" of follicles with growth and development functions. The number of follicles in women has been determined at birth and is non-renewable. With the increase of age and the progress of menstrual cycle, the number of eggs gradually decreases. So how do we evaluate how much "inventory" there is in the ovaries?

1. Age

Age is the primary factor to evaluate fertility, and the best reproductive age for women is 23~32 years old. With the increase of age, fertility gradually decreases, pregnancy rate and live birth rate decrease, and abortion rate increases. With the increase of age, ovarian function declines irreversibly, and the number of follicles and the quality of eggs decrease. Age-related abnormal vascularization, oxidative stress and free radical imbalance in the ovary will lead to the decline of oocyte quality, which will lead to fertilization failure or abnormal embryo development.

The picture comes from the Internet.

2. Basic follicle stimulating hormone (bFSH)

BFSH is the level of serum FSH on the second to fourth day of menstruation, and it is one of the indexes to evaluate ovarian reserve function. The main reasons for the increase of bFSH level are the aging, the decline of ovarian function, the decrease of E2 secretion, the weakening of negative feedback on hypothalamus-pituitary-ovarian axis, and the subsequent increase of FSH. When the serum level of bFSH is higher than 10u/L, the ovarian reserve function is decreased, and when the serum level of bFSH is higher than 18u/L, the live birth rate is almost zero.

3. Basic estradiol (bE2)

BE2 refers to the level of serum E2 on the 2nd to 4th day of menstrual cycle, which can be used as an index to evaluate ovarian reserve function. When the bE2 value is more than 74.9 pg/ml (274.134 pmol/L), the ovarian function is decreased or the pregnancy outcome is poor when in vitro fertilization (IVF) is performed, and the number of embryos obtained is small.

4. FSH/LH (follicle stimulating hormone/luteinizing hormone) ratio

FSH/LH ratio can be used as an index to reflect ovarian function, and can also be used as a sign of ovarian response to gonadotropin to predict pregnancy outcome. When FSH/LH > 2, it is suggested that the ovary may have a bad reaction to gonadotropin in assisted reproductive technology. When FSH/LH > 3.6, the ovarian function is obviously decreased, and the cancellation rate of IVF ovulation cycle is high.

5. Anti-Miller hormone (AMH)

AMH is mainly produced by primary follicles, preantral follicles, sinus follicles, etc. It regulates the growth and development of follicles and is not regulated by hypothalamus-pituitary-ovary axis. As a reliable index of ovarian reserve function, it can be detected on any day of menstrual cycle. Serum AMH concentration was negatively correlated with age. AMH value reaches its peak in adulthood (about 25 years old), generally drops significantly after 36 years old, and approaches zero when approaching menopause.

6. Inhibin B(INH-B)

INH-B appears from the pre-antral follicular phase and is regulated by FSH. INH-B level, as a direct index to predict ovarian reserve function, reflects ovarian reserve. On the third day of menstruation, the blood INH-B < 45 ng/L indicates that ovarian function is decreased.

7. Sinus follicle count (AFC) and ovarian volume

AFC, ovarian volume and ovarian interstitial blood flow parameters can be used as evaluation indexes of ovarian reserve function and responsiveness. AFC is significantly correlated with age and basic hormones. With age, the number of follicles decreases exponentially. Ovarian volume can reflect the number of follicles and the situation of ovarian reserve pool from another angle. With the increase of age, ovarian function declines and ovarian volume shrinks. The most commonly used parameters of ovarian stromal blood flow are the peak velocity of ovarian stromal blood flow (PSV) and resistance index (RI). High PSV and/or low RI indicate that the ovarian interstitial blood supply is abundant and the ovary responds well to gonadotropin.

Second, the evaluation of the structure and function of reproductive tract

Because of the special anatomical structure and physiological function of female reproductive tract, the evaluation of reproductive tract structure and function is also an important link in fertility evaluation, including vagina, cervix, uterus, fallopian tube and pelvic cavity.

1. Detection of vaginal microecology

Female reproductive tract flora is closely related to every step of ovulation, sperm transport, fertilized egg implantation, pregnancy and delivery. Reproductive tract infection of women of childbearing age affects their reproductive health, damages their reproductive function and increases the risk of infertility.

2. Detection of cervical lesions

Cervical diseases tend to be younger, which are closely related to fertility and pregnancy outcome. Regular gynecological physical examination, cervical liquid-based thin-layer cytology (TCT) and human papillomavirus (HPV) screening should be conducted to detect cervical diseases as soon as possible.

3. Detection of uterine abnormalities

Non-invasive ultrasound, such as hysteromyoma and endometrial polyp, is the most widely used examination method to evaluate the receptivity of uterus and endometrium, and to evaluate the shape, thickness, volume, peristalsis wave, uterine artery and hemodynamic parameters of endometrium. Hysteroscopy is the gold standard for the diagnosis of endometrial lesions, which can accurately identify cervical lesions, intrauterine lesions, abnormal endometrial morphology and abnormal tubal opening through endoscopy. Endometrial biopsy can also be performed. At present, there are cytokines, various receptors, endometrial receptivity chips and other detection methods to evaluate endometrial receptivity, and the research on endometrial receptivity is constantly expanding.

4. Tubal patency test

Including salpingostomy, hysterosalpingography/contrast-enhanced ultrasound and laparoscopic salpingostomy. At present, hysterosalpingography has become a research hotspot with its unique advantages (real-time dynamic, visualization and no radiation), and has gradually become the first choice for tubal patency examination. Liquid drainage has some shortcomings, such as invisibility, blindness and great difference. X-ray radiography, as a traditional method of tubal patency examination, mainly has the disadvantages of adverse reaction of contrast agent and radiation damage. Laparoscopic salpingostomy is the "gold standard", but it is not the first choice for the time being because of invasion, hospitalization, high cost, surgery and anesthesia.

The picture comes from the Internet.

5. Detection of pelvic factors

Pelvic diseases are closely related to female fertility, such as pelvic endometriosis, pelvic tuberculosis, pelvic adhesion, tubal diseases, hysteromyoma, ovarian tumors and pelvic inflammatory diseases. Laparoscopic surgery can find and diagnose abnormal pelvic conditions in time. For infertility caused by fallopian tube factors or uterine cavity factors, hysteroscopy combined with laparoscopy can treat pelvic cavity, fallopian tube and uterine cavity diseases accordingly, which has important clinical value for female fertility evaluation, diagnosis and treatment.

6. Female reproductive tract dysplasia

Abnormal development of female reproductive tract includes abnormal development of vagina, cervix, uterine body and fallopian tube, with or without abnormalities of ovary and urinary system. The combination of pelvic ultrasound and MRI examination is the best examination method for reproductive tract dysplasia.

Third, the general state assessment

In terms of systemic diseases, we should evaluate whether there are diseases that affect fertility or are not suitable for fertility, such as thyroid diseases, familial genetic diseases, blood system diseases, cardiopulmonary diseases and tumors.

1. Thyroid diseases

Abnormal thyroid function can lead to infertility and poor pregnancy outcome, so it is suggested that women with family planning should monitor thyroid function. Clinical hyperthyroidism can lead to abortion, premature delivery and thyroid crisis, and timely treatment can significantly reduce these risks; Infertile women with subclinical hypothyroidism should be treated with levothyroxine (LT4).

2. Hereditary diseases

According to the etiology, it can be divided into monogenic diseases, polygenic diseases, chromosomal diseases, mitochondrial genetic diseases and somatic genetic diseases, which have the characteristics of congenital, lifelong and familial. It is suggested that couples with rare diseases or couples who have given birth to rare diseases should have genetic testing and genetic counseling, reproductive risk assessment and guide reproductive decisions. The genetic diagnosis (PGD) before embryo implantation was provided after the pathogenic gene locus and genetic mode of the family were clarified.

3. Other general conditions

Nutritional status is a very important factor in regulating reproductive process, which is closely related to female reproductive function. For example, obesity and malnutrition have adverse effects on internal environment, egg quality and embryo development. In addition, mental state, living environment and systemic factors also need comprehensive consideration. Whether a woman’s whole system can withstand pregnancy is also the concern of fertility evaluation, including whether she is complicated with diabetes, hypertension, heart disease and tumor.

4. Who needs fertility assessment?

1. Couples who have been pregnant for more than 1 year without pregnancy;

2. People who have had many bad pregnancies in the past;

3. People who have had multiple abortions or ectopic pregnancy in the past;

4. Women of childbearing age with less menstrual flow, irregular menstrual cycle and dysmenorrhea;

5. Obese or thin people (BMI>24 or BMI<18.5);

6. White-collar workers who stay up late and work overtime for a long time;

7. People who use computers and mobile phones for a long time to work in a radiation environment;

8. People with smoking, drinking, drug addiction and other habits.

In a word, fertility assessment can help women understand their fertility potential and possible fertility problems. In fact, whether you have the desire to have children at present or not, regular fertility assessment can help you plan your birth plan reasonably, receive corresponding medical help in time, and don’t leave regrets for your life!

Do you eat healthier in 2019?

As the Spring Festival approaches, law enforcement officers of the Yushui District Market Supervision Bureau in Xinyu City, Jiangxi Province conduct on-site rapid detection of vegetable pesticide residues at Guanxia Smart Farmers Market. Photo by Liao Haijin/Bright Picture

A college student food festival was held in Shanghai. The picture shows the "fleshy" Mu Si cake as a dessert in the dining hall of Shanghai Ocean University. Xinhua news agency

Citizens and tourists visit the Chongqing New Year Food Festival. Xinhua news agency

Villagers in Kangzhuang Village, Qukou Town, Xianghe County, Hebei Province are drying red and white sausages. Xinhua news agency

  Is "artificial meat" edible? Is online celebrity food reliable? Are probiotics really useful? What foods have you paid attention to in the past 2019? What troubles have they brought you? Food safety concerns people’s health and life safety. At the "Media Communication Meeting on Scientific Interpretation of Food Safety and Health Hotspots in 2019", which was directed by China Association for Science and Technology and hosted by chinese institute of food science and technology recently, experts combed and interpreted the hot events of food safety that the public paid attention to in the past year, and made suggestions for food safety supervision by popularizing food safety knowledge through examples. This edition extracts some hot topics to interpret.

"artificial meat"

Scientific and technological problems to be solved, standards and regulations to be improved.

  Interpretation expert: Wang Shouwei (Director of China Meat Food Comprehensive Research Center and Dean of Beijing Food Science Research Institute)

  "Artificial meat" is synonymous with foods that are not naturally produced and have a similar taste to meat. It is usually divided into two categories: vegetable protein meat and cell cultured meat. The emergence of "artificial meat" on the one hand is to meet the rapidly growing meat demand of consumers, on the other hand, it provides a way to effectively reduce the land occupation of animal husbandry, the use of water resources and greenhouse gas emissions, and solve the problems of environmental protection and sustainable development.

  In recent years, the processing technology of vegetable protein meat is becoming more and more mature at home and abroad, and many enterprises have developed vegetable protein meat products with vegetable protein as raw materials. The research on using animal stem cells to produce cells to cultivate meat has also made great progress, and many enterprises have announced that they can develop cells to cultivate meat in the laboratory. Vegetable protein meat has great market potential and a high degree of commercialization. In the future, developing products more similar to real meat has become a direction for the food industry and scientific and technological circles.

  In the innovation and development of "artificial meat", it is necessary to increase scientific and technological input and solve the existing scientific and technological problems of "artificial meat". For example, research on the formation mechanism, raw material supply and processing technology of vegetable protein meat should be carried out to build a new research and development system. In the process of industrialization, we pay attention to improving the flavor, texture and nutrition of products, and constantly meet the increasingly diversified needs of consumers. Carry out research on the basic theory and key production technology of cell-cultured meat, and establish a production technology system of cell-cultured meat suitable for human food manufacturing.

  While innovating and developing, adhering to product quality and safety is the foundation of the development of "artificial meat". It is suggested that the new ingredients and new production technology added in the production of "artificial meat" should be systematically evaluated for safety, and an independent standard system and an objective supervision system should be formed in the evaluation of product safety and nutritional components, so as to promote the benign development of the industry.

  Scientific and rigorous standards are the cornerstone of the healthy development of the industry. In China, the development momentum of vegetable protein meat industry has been formed, and the product categories are relatively mature, but the existing laws and regulations are not suitable for product innovation and industry development; The development of its standard should be carried out as soon as possible, and the definition, classification method and production technology should be clearly defined, which will provide convenience for government supervision and provide reference for the direction of production and innovation of products in the industry. In addition, the research and development of cell-cultured meat in China is still in its infancy, but the development speed is very fast, and the research on standards and supervision methods has just begun; The division of supervisory responsibilities and division of labor system should be clarified, and a strict system of standards and laws should be formed. In addition, public science popularization should be carried out to guide consumers to correctly understand and rationally consume "artificial meat".

Online celebrity food

Strictly guard against the transformation of "red and black"

  Interpretation expert: Ma Guansheng (Head of the Department of Nutrition and Food Hygiene, Peking University College of Public Health)

  Some sellers make use of social media’s special publicity and marketing methods to dress up homemade food as "online celebrity" food, which is popular in the circle of friends. From home-made delicious food to home-brewed fruit wine, from morning tea snacks to midnight snacks, from beauty soup to dietary remedies, there are all kinds of foods in the circle. Online food attracts waves of consumers with its novel appearance, photos or taste. However, when consumers buy food, they often ignore the quality of the food itself, including raw materials, production date, shelf life and production address.

  Due to the special sales channels (such as WeChat circle of friends, micro-stores), online celebrity food has some problems, such as difficult management and lack of effective supervision mechanism. Taking the incident of "there is no milk in milk tea" in online celebrity as an example, China’s national standard "Tea Beverage" (GB/T 21733-2008) defines milk tea drinks and milk tea-flavored drinks as liquid drinks prepared by taking water extract of tea or its concentrated solution and tea powder as raw materials and adding one or more of milk or dairy products, sugar and/or sweeteners, edible milk flavor essence, etc. Although there is a requirement for the protein content of milk tea in this standard (&ge; 0.5%), but milk or dairy products are still only one of a variety of optional ingredients, not a hard requirement. Therefore, due to the lack of clear standards for existing milk tea, there is an embarrassing situation that "milk tea does not contain milk", which increases the maneuverability of merchants and brings blind spots to food safety supervision.

  It is suggested to improve the supervision mechanism and clarify the responsibilities and supervision methods of all parties in the business activities of non-traditional foods such as online food sales. At the same time, strengthen regular sampling and random inspection, and urge network platforms and production operators to implement the main responsibility. Strike hard at illegal food safety behaviors in online sales, strictly investigate and deal with behaviors such as "brushing the bill" and "false comments", and protect consumers’ rights and safety with strict supervision.

  Online celebrity food is mainly sold through the online platform, so the online platform should assume the responsibility of screening and supervision. The network platform should establish a mechanism to help the superior and limit the inferior, strictly control the entry threshold of merchants, inspect and regularly review their retail qualifications and relevant licenses for selling products, and prevent counterfeit and shoddy foods from being sold on the network platform. Food enterprises and individual food producers should strengthen the construction of industrial chain safety, ensure the safety and traceability of product sources, make the product chain clear, and prevent and control risks. As consumers themselves, they should constantly improve their health literacy and food safety literacy, make rational purchases, and not blindly "chase after the red".

probiotics

The efficacy has the specificity of strains and people.

  Interpretation expert: Chen Wei (Academician of China Academy of Engineering, Chairman of Probiotics Branch of chinese institute of food science and technology, Vice President of Jiangnan University); He Guoqing (Vice Chairman of chinese institute of food science and technology Probiotics Branch, Professor of Zhejiang University)

  Probiotics have a strict definition: they must be living microorganisms, which are beneficial to the health of the host when ingested in sufficient quantities. Moreover, the health function of probiotics should be based on scientific and rigorous clinical trial evaluation and evidence-based medical evidence. At present, tens of thousands of published academic papers have studied the functions of different probiotic strains, confirming that the core function of probiotics is to improve the health of human gastrointestinal tract. In addition, in vitro experiments such as cell model, animal experiments and human experiments show that probiotics may have potential beneficial functions to improve metabolism and nervous system. However, in vitro experiments and the actual human digestive system are completely different worlds, and the results of in vitro experiments can never be used to claim the functions of probiotics. Animal experiments can be used as a reference, but it needs to be confirmed by large-scale and deeper human or clinical experiments.

  It is a long-term, rigorous and scientific process for human beings to explore the efficacy of probiotics. At present, there are various probiotic products with claimed functions on the market. However, it should be emphasized that the academic community has reached a consensus that the core function of probiotics is to improve gastrointestinal health.

  Generally speaking, the mainstream probiotic strains in the market are all isolated from healthy people and fermented foods with a long history of safe use. Most of them are considered as non-pathogenic symbiotic microorganisms, and their safety has been recognized by authoritative organizations. Of course, for sick individuals, such as patients with severe infection or immunodeficiency, they should be used with caution or consult a doctor.

  It should also be noted that the efficacy of probiotics has the specificity of strains and people. There are differences in probiotic efficacy among different strains; There are also differences in physiological regulation of probiotics among different hosts. Therefore, in the future, we should confirm the relevant probiotic functions at the strain level, judge and apply the individual functions of probiotics according to the individual characteristics of different hosts, and pay attention to personalized precise nutrition. Of course, the industrial application of probiotics must also be verified by scientific and rigorous processes. For example, the species, even the genetic composition and basic physiological and biochemical characteristics of the strain are first studied, and then the adaptability, safety and probiotic characteristics of the strain are evaluated in turn, and finally the probiotic dosage and probiotic combination with satisfactory efficacy are selected.

  In addition, consumers should choose probiotic-related products scientifically and reasonably. For lactic acid bacteria drinks, consumers should pay attention to distinguish product types when purchasing. According to the relevant standards in China, the labels of lactic acid bacteria drinks should be marked with live bacteria (non-sterilization) or non-live bacteria (sterilization), and they can be distinguished by labels when purchasing. When consumers buy yogurt, they should keep it reasonably according to the label. Low-temperature yogurt should be sold in cold storage. When they return home after purchase, they should put it in the refrigerator as soon as possible and drink it in time to ensure its strain activity.

  Probiotics have individual differences in their effects on health, and there is no "all-purpose" probiotic strain, which is suitable for everyone and all physical conditions. We should further strengthen the popular science education of consumers, popularize the professional knowledge of probiotics and clarify the scientific concept of "quantity" of probiotics, so that consumers can rationally choose probiotic products.

Self-heating food

It is necessary to cross the safety hurdle of "self-heating package"

  Interpretation expert: Lu Fuping (Vice President of chinese institute of food science and technology and Vice President of Tianjin University of Science and Technology)

  Self-heating food is a product that heats food with flameless self-heater and quickly reheates it to edible state. In recent years, a series of self-heating products represented by self-heating hot pot have developed rapidly. Besides the common self-heating hot pot and self-heating rice, there are also self-heating porridge, noodles, rice noodles, soup, etc., which are diverse and meet the urgent needs of consumers for hot food in more consumption scenarios.

  Although the safety of self-heating food is generally controllable, the safety risk of "self-heating package" should be paid full attention to. Since self-heating food uses the chemical reaction between heating agent and water to generate heat to heat the food. Occasional phenomena such as "self-heated food rupture" or "unstable temperature of self-heated food" have aroused people’s concern about the safety of self-heated food.

  Under the current self-heating technology in China, the chemical self-heating package used for self-heating food is mostly magnesium/iron for military use and aluminum-water for civilian use. No matter what kind of heating package, a small amount of hydrogen will be produced when heating. If individuals eat or a small number of people gather to eat, even in a closed environment, the amount of hydrogen generated by the heating of the heating package is far from the limit that can cause explosion. Under normal circumstances, the normal products will be eaten according to the normal operating procedures, and there will be no risk and safety problems such as cracking. However, if people eat a lot of self-heating food at the same time in a closed environment, or if the vent hole on the self-heating food packaging box is blocked, there may be potential safety hazards, which need to be paid full attention to.

  It is suggested to increase the research on the safety of self-heating package and develop a self-heating package with high efficiency and good safety. By developing energy-efficient formula and new heating device, the generation of hydrogen and water vapor can be controlled or reduced, the demand for energy efficiency release and utilization can be improved, and the safety level can be improved. Develop a new type of physical self-heating device, use renewable energy and reduce pollution. In addition, it is necessary to enhance the effectiveness and support ability of the self-heating device in various scenarios.

  The rapid development of self-heating food industry has attracted a large number of enterprises to join. However, due to the imperfect standards and specifications of self-heating food, the enterprises that have joined the self-heating food industry are mixed, which seriously affects the healthy development of the industry. At present, only the group standard "Self-heating Convenient Cuisine Products" issued by China Business Federation in 2017. From the perspective of regulating the industry, self-heating food needs more stringent standards to ensure its healthy development. It is understood that the industry is actively exploring how to establish a unified standard, for example, by standardizing the chemical composition and proportion, heating intensity, hydrogen production and other indicators contained in self-heating food heating packages, and making clear requirements for the treatment of final waste, so as to improve the entry threshold of the industry and standardize the healthy development of the industry.

Special medical food

Not for everyone

  Interpretation expert: Ren Fazheng (Academician of China Academy of Engineering, Vice Chairman of chinese institute of food science and technology Probiotics Branch, Professor of China Agricultural University)

  Special medical food is formula food for special medical use, which is specially processed and prepared to meet the special needs of people with limited eating, digestive and absorption disorders, metabolic disorders or specific disease States for nutrients or meals. It also has a very strict classification, which is currently divided into two categories: people aged from 0 months to 12 months and people over 1 year old.

  On the basic functions of special medical food &mdash; &mdash; At present, there is a broad consensus on nutritional support, including improving the treatment and rehabilitation effect, shortening the course of disease, reducing medical expenses, increasing the turnover rate of hospital beds, and reducing the readmission rate, which can be solved through nutritional support and special medical food. The World Health Organization has proposed that if more money is invested in nutrition and health care, less 8.5 yuan can be spent on treatment and the cost of rescue in 100 yuan can be saved. It can be said that the nutritional support function of special medical food is indispensable in clinic. Of course, it can’t replace drugs.

  Special medical food is a new industry in our country, and our government attaches great importance to it, and has made very strict management regulations at the beginning of the industry development. Special medical food should be registered by the food safety supervision and administration department of the State Council, and the formula of special medical food should be based on the research results of medicine and nutrition, and its safety and clinical application effect need to be scientifically confirmed.

  According to news reports, some illegal enterprises produce ordinary solid drinks, pass off as special medical milk powder and mislead consumers. This kind of behavior belongs to false propaganda, which should be severely cracked down and strengthened management. In addition, when the special medical food is registered and put on record, the product formula and production technology are strictly regulated. Food enterprises should produce special medical food according to the registered formula, and cannot produce special medical food without obtaining the registered formula and production license.

  The demand emphasizes that special medical food is special and not suitable for everyone. Moreover, different special people need different special medical foods. We should strengthen the popularization of special medical food, let consumers know its particularity and eat it according to the doctor’s advice.

Reduce salt, oil and sugar

Science and technology lead, scientific implementation

  Interpretation expert: Chen Junshi (Academician of China Academy of Engineering, General Consultant of National Food Safety Risk Assessment Center)

  The diet of Chinese residents is high in salt, oil and sugar. "Three reductions" is not an isolated matter, it is an important part of the whole reasonable diet. Whether it is the government supervision department, food industry or consumers, it is necessary to raise awareness and establish the concept of "reasonable diet".

  Carrying out the "three reductions" action is not a matter for any department or enterprise, but should be coordinated and promoted by all parties. The government should formulate corresponding policies to lead the "three reductions" action, and catering and food processing enterprises should provide diversified products with different levels of salt, oil and sugar for consumers to choose by reducing the use of salt, oil and sugar. Residents gradually reduce the use of salt, oil and sugar in their daily cooking.

  In particular, the food industry and catering industry should accelerate the transformation and upgrading of nutrition according to the health needs of consumers, and take the initiative to take measures to reduce the use of salt, oil and sugar in food. This requires increasing scientific and technological support, laying a solid scientific foundation, solving the problems such as product flavor change and shortened shelf life that may be caused by "three reductions", innovating and developing new foods, and leading a healthy transformation with science and technology. In addition, there are different dietary nutrition problems in different regions and different groups of people, so nutrition science education should be targeted and reflect differentiation. Nutrition intervention should be precise, and the implementation of policies should be based on science and practical. Focus on guiding enterprises to provide more differentiated products for consumers to choose, and guide consumers to choose products that suit them reasonably.

  The action of "three reductions" needs to be carried out step by step in line with China’s national conditions, instead of "eating a fat man at one breath". It takes time to change people’s tastes, not quick. The improvement of cooking, methods and food processing technology also takes time, which cannot be achieved overnight, and should be carried out step by step in accordance with scientific laws. The transformation of consumer health concept needs long-term positive guidance and popularization of scientific knowledge. Therefore, the implementation of the "three reductions" action must be gradual, and various problems must be solved step by step.

Food fraud

Counterfeiting detection technology needs to be upgraded

  Interpretation expert: Wu Yongning (Chairman of chinese institute of food science and technology Food Authenticity and Traceability Branch, Technical Chief of National Food Safety Risk Assessment Center); Chen Ying (Vice President and Chief Engineer of China Academy of Inspection and Quarantine)

  Food quality, food safety and food truth are three attributes of food. The authenticity problems such as food fraud and forgery exist at home and abroad. For example, as the saying goes in China, "selling dog meat by hanging sheep’s head" and the "horse meat passing off as beef" that happened in Europe a few years ago. The World Health Organization once pointed out that apart from food-borne diseases, more and more food fraud and food fraud problems need to be paid attention to.

  Ensuring the authenticity of food is not only to protect public health, but also a necessary measure to curb the market chaos of "bad money drives out good money", standardize the market competition order and boost food consumption confidence. At present, China has basically met the public’s requirements for the quantity and quality of food, and the concern for food safety has reached a higher level. However, for a long time, the investment in food authenticity technology is relatively lacking, and it is difficult to guarantee the scientific supervision of "food authenticity". If food fraud is "a magic height of one foot", then the detection technology of counterfeit identification must be "a magic height of one foot".

  It is suggested to increase the scientific and technological investment in food authenticity research and overcome the technical difficulties and supervision problems of food authenticity. At the same time, speed up the transformation of technical standards of food authenticity, formulate corresponding detection methods and standards, and provide technical support for scientific supervision of food authenticity in China.

  (This edition of the article was compiled by our reporter Chen Haibo)

Central Meteorological Observatory: Heavy rain and strong convection warning are all in full swing, and the high temperature tolerance in Huanghuai and other places in North China is full.

  Cctv newsAccording to the Central Meteorological Observatory, yesterday, heavy rainfall mainly occurred in eastern Sichuan, northwestern and southwestern Shaanxi, central Shanxi, northeastern Shandong, central Guangxi, eastern Guangdong and other places, including Chengdu, Mianyang and Guangyuan in Sichuan, Hanzhong in Shaanxi, Baise in Guangxi and Shanwei in Guangdong. Thunderstorms or hailstorms occurred in southern Ningxia, north-central Shaanxi, western Shanxi, and central and eastern Shandong. It is estimated that there will be heavy rain or rainstorm in the southwestern Shaanxi, eastern Sichuan Basin, Jianghan, Jianghuai, northern Jiangnan, eastern Huanghuai, eastern North China, southern Liaoning and northern Heilongjiang on the 28th to 30th, with local heavy rain accompanied by obvious strong convective weather. The Central Meteorological Observatory continued to issue a blue warning for heavy rain and strong convective weather this morning.

  Today, there are heavy rainstorms in Liaodong Peninsula, eastern Beijing, northern Tianjin, northeastern Hebei, central and eastern Shandong, eastern Sichuan, southwestern Shaanxi, most of Chongqing and western Hubei, among which there is heavy rain (100-140 mm) in northern Chongqing, accompanied by short-term heavy rainfall (the maximum hourly rainfall is 30-50 mm, and the local area can exceed 60 mm). Parts of northeastern Inner Mongolia, southwestern Heilongjiang, central and western Jilin, southern Liaoning, southeastern Shaanxi, eastern Hebei, eastern Beijing, Tianjin, northern and eastern Shandong, northern Anhui, northern Jiangsu and other places will have 8-10 thunderstorms or hail weather, and the local wind can reach 11.

  The public should pay attention to the weather in time, prevent the adverse effects of heavy rainfall and local strong convective weather on traffic travel, and stay away from areas with high risk of meteorological disasters.

  In addition, it is expected that there will still be many hot weather in North China, Huanghuai and other places in the next two weeks, with the main high temperature periods from June 29 to July 2 and July 6-10. The daily maximum temperature in central Inner Mongolia, North China, Huanghuai and Fenwei Plain will be 35℃ ~ 39℃, and the local temperature can reach 41℃. High temperature weather is full of endurance, so the public should pay attention to temperature changes, reduce outdoor activities, take measures to prevent heatstroke and heat stroke.

At 10: 00 on July 28, the Central Meteorological Observatory continued to issue an orange rainstorm warning.

  Cctv newsThe Central Meteorological Observatory continued to issue an orange rainstorm warning at 10: 00 on July 28th.

  It is estimated that there will be heavy rains in parts of Fujian, eastern Jiangxi, eastern and southern Zhejiang, central and southern Anhui, southern Hebei, most of Shandong, central and northern Henan, eastern Gansu, central Shaanxi, northern Hubei, western and southern Yunnan, among which there will be heavy rains in parts of southern Anhui, northwestern Jiangxi, central and southern Zhejiang and most of Fujian, and in southeastern Fujian. Some of the above areas are accompanied by short-term heavy rainfall (the maximum hourly rainfall is 30 ~ 60 mm, and the local area can exceed 80 mm), and there are strong convective weather such as thunderstorms and strong winds.

  Defense guide:

  1, the government and relevant departments in accordance with their duties to do a good job in emergency work against heavy rain;

  2. Cut off the dangerous outdoor power supply and suspend outdoor work;

  3. Units in danger zones shall suspend classes or business, and take special measures to protect the safety of students, children and other working personnel who have arrived at school;

  4, do a good job in urban and farmland drainage, pay attention to prevent possible disasters such as flash floods, landslides and mudslides.

Audi has finally made efforts, a conscientious "worker"

Although Audi Q4 e-tron is not excellent, it can reach the mainstream level of the same level. The strength of the car still needs to be understood before we know, so let’s take a look.

Let’s take a look at the appearance of the Audi Q4 e-tron. The front of the Audi Q4 e-tron looks very calm and deep. Then the fashionable headlight design is adopted, which is very sporty. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, delayed closing, rain and fog mode and so on. Come to the side of the car, the car body size is 4588MM*1865MM*1626MM, the car uses rounded lines, the car side gives people a very avant-garde feeling, with large-size thick-walled tires, eye-catching shape. In the rear part, the overall shape of the rear part echoes the front face, the taillight style is more individual, and the overall layout is impressive.

In terms of interior, the interior of Audi Q4 e-tron presents a concise design style, and the overall design atmosphere is still in place. The steering wheel of the car is very in line with the interior style, made of genuine leather and has a high palm fit. Let’s take a look at the central control. The design of the center console is reasonable, which makes the interior style impressive, and the details are still in place. The interior feels good. Let’s take a look at the dashboard and seats. The dashboard design is remarkable and gives people a very lovely feeling. The car uses a mix of leather/suede seats, and the seat wrapping is in place and the comfort is acceptable.

Audi Q4 e-tron matching gearbox, 100 km acceleration time is 6.8s, and the power is completely OK for daily use.

Equipped with car networking, driving mode selection, remote control key, rear wiper, interior atmosphere light and other configurations, the configuration has reached the mainstream level of the same level.

The model class introduced today is the most considered class when many people buy their first car, mainly because the size of this class is moderate and the price is reasonable. If you are interested, you might as well experience it.

Statistical Report on Loan Investment of Financial Institutions in the First Quarter of 2022

According to the website of the central bank, according to the statistics of the People’s Bank of China, at the end of the first quarter of 2022, the balance of RMB loans of financial institutions was 201.01 trillion yuan, up 11.4% year-on-year; In the first quarter, RMB loans increased by 8.34 trillion yuan, an increase of 663.6 billion yuan.

First, the loans of enterprises and institutions grew steadily, and the interest rate of new corporate loans was at a low level.

At the end of the first quarter of 2022, the loan balance of local and foreign currency enterprises and institutions was 129.83 trillion yuan, up 11.8% year-on-year, and the growth rate was 0.8 percentage points higher than the end of last year; In the first quarter, it increased by 7.25 trillion yuan, an increase of 1.69 trillion yuan.

In terms of terms, the balance of short-term loans and bill financing was 47.37 trillion yuan, up 11.5% year-on-year, and the growth rate was 5.3 percentage points higher than that at the end of last year. In the first quarter, it increased by 3.2 trillion yuan, an increase of 2.28 trillion yuan. The balance of medium and long-term loans was 79.14 trillion yuan, up 12.2% year-on-year, and the growth rate was 1.8 percentage points lower than the end of last year. It increased by 3.96 trillion yuan in the first quarter, a year-on-year decrease of 514.4 billion yuan.

In terms of purposes, the balance of fixed assets loans was 54.95 trillion yuan, a year-on-year increase of 9.5%, and the growth rate was 0.6 percentage points lower than that at the end of last year; The balance of operating loans was 52.73 trillion yuan, a year-on-year increase of 9.6%, and the growth rate was 0.2 percentage points lower than the end of last year.

In March, the interest rate of new corporate loans was 4.37%, which was 8 and 19 basis points lower than that at the beginning of the year and the same period of last year respectively.

Second, the growth rate of medium and long-term loans in industry is relatively high, and the growth rate of medium and long-term loans in infrastructure industry is stable.

At the end of the first quarter of 2022, the balance of medium-and long-term loans in local and foreign currency industries was 14.39 trillion yuan, up 20.7% year-on-year, and the growth rate was 9.7 percentage points higher than that of various loans and 1.9 percentage points lower than that at the end of last year. In the first quarter, it increased by 940.9 billion yuan, an increase of 24.9 billion yuan. Among them, the balance of medium and long-term loans for heavy industry was 12.32 trillion yuan, up 19.7% year-on-year, and the growth rate was 1.8 percentage points lower than that at the end of last year; The balance of medium and long-term loans for light industry was 2.07 trillion yuan, up 27.1% year-on-year, and the growth rate was 2 percentage points lower than that at the end of last year.

At the end of the first quarter of 2022, the balance of medium and long-term loans in local and foreign currency service industries was 52.22 trillion yuan, up 9.2% year-on-year, and the growth rate was 1.8 percentage points lower than that at the end of last year. It increased by 2.3 trillion yuan in the first quarter, a year-on-year decrease of 470.3 billion yuan. The balance of medium and long-term loans in the real estate industry decreased by 1.5% year-on-year, and the decline was 1 percentage point higher than the end of last year.

At the end of the first quarter of 2022, the balance of medium and long-term loans in local and foreign currency infrastructure was 30.26 trillion yuan, up 13.2% year-on-year, and the growth rate was 2.2 percentage points higher than that of various loans; It increased by 1.39 trillion yuan in the first quarter, a year-on-year decrease of 251.3 billion yuan.

3. Loans in inclusive finance maintained a relatively rapid growth rate, the proportion of credit loans increased, and the interest rate of new loans continued to decrease.

At the end of the first quarter of 2022, the balance of RMB loans in inclusive finance was 28.48 trillion yuan, a year-on-year increase of 21.4%, 1.8 percentage points lower than the end of the previous year; In the first quarter, it increased by 1.98 trillion yuan, an increase of 17.8 billion yuan.

At the end of the first quarter of 2022, the balance of Pratt & Whitney small and micro loans was 20.77 trillion yuan, a year-on-year increase of 24.6%, and the growth rate was 2.7 percentage points lower than that at the end of last year, of which credit loans accounted for 18.9%, 0.8 percentage points higher than that at the end of last year; It increased by 1.55 trillion yuan in the first quarter, a year-on-year decrease of 24.1 billion yuan. The balance of loans for farmers’ production and operation was 7.25 trillion yuan, a year-on-year increase of 14.1%; The balance of business guarantee loans was 251.3 billion yuan, up 11% year-on-year; The balance of student loans was 143.4 billion yuan, a year-on-year increase of 12.3%. In March, the interest rate of new loans for Pratt & Whitney small and micro enterprises was 4.93%, 17 basis points lower than that at the beginning of the year.

At the end of the first quarter of 2022, the balance of loans for people out of poverty nationwide was 953.7 billion yuan, up 16.5% year-on-year, and increased by 39.7 billion yuan in the first quarter.

Fourth, green loans maintained rapid growth.

At the end of the first quarter of 2022, the balance of green loans in local and foreign currencies was 18.07 trillion yuan, up 38.6% year-on-year, 5.6 percentage points higher than the end of last year, and 27.6 percentage points higher than the growth rate of various loans, with an increase of 2.05 trillion yuan in the first quarter. Among them, loans to projects with direct and indirect carbon emission reduction benefits were 7.79 and 4.22 trillion yuan respectively, accounting for 66.5% of the total green loans.

In terms of purposes, the loan balances of green upgrading industry of infrastructure, clean energy industry and energy conservation and environmental protection industry were 8.27, 4.74 and 2.32 trillion yuan respectively, up by 31.3%, 39.3% and 58% respectively. In terms of industries, the balance of green loans in electricity, heat, gas and water production and supply industries was 4.82 trillion yuan, up 29.2% year-on-year, and increased by 342.7 billion yuan in the first quarter; The balance of green loans in transportation, warehousing and postal services was 4.36 trillion yuan, up 13.2% year-on-year, and increased by 233.4 billion yuan in the first quarter.

V. The growth rate of agriculture-related loans remained stable.

At the end of the first quarter of 2022, the balance of agricultural loans in local and foreign currencies was 45.63 trillion yuan, up 12.2% year-on-year, and the growth rate was 1.3 percentage points higher than that at the end of last year. In the first quarter, it increased by 2.61 trillion yuan, an increase of 560.3 billion yuan.

At the end of the first quarter of 2022, the balance of rural loans (at or below the county level) was 38.13 trillion yuan, a year-on-year increase of 12.8%, and the growth rate was 0.7 percentage points higher than that at the end of last year; In the first quarter, it increased by 2.14 trillion yuan, an increase of 323.2 billion yuan. The balance of farmers’ loans was 14.05 trillion yuan, up 12.9% year-on-year, and the growth rate was 1.1 percentage points lower than the end of last year. It increased by 624.8 billion yuan in the first quarter, a year-on-year decrease of 30.9 billion yuan. The balance of agricultural loans was 4.84 trillion yuan, up 8.4% year-on-year, and the growth rate was 1.3 percentage points higher than that at the end of last year. In the first quarter, it increased by 280.3 billion yuan, an increase of 76.8 billion yuan.

Six, real estate development loans increased month-on-month, personal housing loan interest rates fell.

At the end of the first quarter of 2022, the balance of RMB real estate loans was 53.22 trillion yuan, a year-on-year increase of 6%, which was 1.9 percentage points lower than the growth rate at the end of last year; In the first quarter, it increased by 779 billion yuan, accounting for 9.3% of the increase of various loans in the same period, accounting for 9.8 percentage points lower than the level of the previous year.

At the end of the first quarter of 2022, the balance of real estate development loans was 12.56 trillion yuan, down 0.4 percentage points year-on-year, and the growth rate was 1.3 percentage points lower than that at the end of last year; The first quarter increased by 290 billion yuan, an increase of 441.4 billion yuan over the fourth quarter of last year. The balance of individual housing loans was 38.84 trillion yuan, up 8.9% year-on-year, and the growth rate was 2.3 percentage points lower than the end of last year. In March, the interest rate of new personal housing loans was 5.42%, 17 basis points lower than that at the beginning of the year.

Seven, the growth rate of household loans slowed down, and the interest rate of consumer loans dropped sharply.

At the end of the first quarter of 2022, the balance of household loans in local and foreign currencies was 72.37 trillion yuan, up 10.1% year-on-year, and the growth rate was 2.4 percentage points lower than that at the end of last year. In the first quarter, it increased by 1.26 trillion yuan, a year-on-year decrease of 1.3 trillion yuan.

At the end of the first quarter of 2022, the balance of operating loans of local and foreign currency households was 17.1 trillion yuan, up 16% year-on-year, 3.1 percentage points lower than the end of last year; In the first quarter, it increased by 888.7 billion yuan, a year-on-year decrease of 241.4 billion yuan. The balance of other consumer loans (excluding personal housing loans) was 16.42 trillion yuan, up 7.1% year-on-year, and the growth rate was 2.4 percentage points lower than that at the end of last year. It decreased by 150.2 billion yuan in the first quarter, a year-on-year decrease of 358.5 billion yuan. In March, the interest rate of new household other consumption loans was 7.68%, which was 67 and 41 basis points lower than that at the beginning of the year and the same period of last year respectively.

Sogou input method has the function of "help you chat", which allows users to express themselves accurately and quickly.

Do you often feel distressed by the lack of literary talent in online communication language expression? Do you often weigh your words but still don’t know how to reply to your friends’ messages properly? 

Recently, sogou’s input method was updated to the new version of 10.9, and the intelligent Wang Zi function of AI assistant was upgraded again, and the exclusive and original "Help You Chat" function was launched, which helped users to open the skills of god chat, allowing users to express themselves accurately and quickly.

Picture 1.png 

As early as August, 2019, sogou Input Method innovatively introduced AI assistant into input method products, released AI intelligent Wang Zi assistant, and launched functions such as expression recommendation, quip recommendation, information recommendation, weather recommendation, etc. to help users express smoothly and efficiently in different scenarios, which significantly improved the user’s input experience.

It is understood that after the launch of the "Help You Chat" function, the AI ? ? intelligent assistant Wang Zi is more intelligent, which can not only help users chat more smoothly, but also make users chat more interesting.

After the new version of sogou Input Method 10.9 went online, AI intelligent assistant Wang Zi upgraded from the original intelligent "replacement" of user chat content to intelligent "completion" of user chat content, making users express more efficiently and accurately without thinking. For example, when you enter "hahaha", the "Help You Chat" function will suggest the user to input the completed content according to the scene intelligence, and the user can choose to send it to the chat friend with one click.

Picture 2.png

Not only that, the "help you chat" function can also assist users to express their interest in poetic language. For example, when the user inputs any two words, click on the quip recommendation, and the AI intelligent assistant Wang Zi will recommend to the user a "poem" composed by AI with the input content. This makes the chat content more personalized, highlights personal aesthetic taste, and makes the chat content poetic and more interesting.

Picture 3.png

From recommending chat content for users to assisting users to chat, and intelligently optimizing and completing users’ chat content, sogou AI intelligent Wang Zi assistant has once again evolved, which is inseparable from the continuous innovation and progress of sogou AI technology. It is reported that after the new version is launched, after the user turns on the "Help You Chat" function, the recommended content will be 100% when the user inputs it, and the recommended content varies from person to person, with thousands of people, and everyone’s content is all original for AI, so that users can talk about tricks and new ideas.

As a well-deserved "leading brother" in the domestic input method field, sogou input method has never stopped the pace of product innovation. Focusing on the vision of making it easier to express and obtain information, sogou first applied AI technology to input method products to help users express more simply, efficiently and interestingly, which not only made the user experience of sogou input method always ahead of the industry, but also laid the leading position of sogou input method in the AI era.

With the launch of the original "help you chat" function, sogou input method once again leads the new direction of AI input. In the future, with AI empowerment, the input method will not only be a tool to improve people’s expression efficiency, but also an essential assistant to improve people’s work efficiency and increase the fun of life.

Shared office is coming: the cost of starting a business by renting a seat is reduced.

  Lu Yishe (people’s vision)

  Core reading

  In the 2017 "Government Work Report", it was proposed to "support and guide the sharing of economic development". At present, bike-sharing and shared cars are developing rapidly, and shared office is also on the rise. So, what is shared office? For enterprises and society, what value and prospect does shared office mean? Please see the reporter’s field investigation in Shanghai.

  Save money and time.

  ■ A seat can be rented, and startups can also work in the city center.

  Cheng Yin never thought that the office was done so quickly, and it was in Jing ‘an District in the center of Shanghai!

  "A person’s office, rent an office? It’s hard to think about it. However, if you find WEWORK, you will get it in one go. " Cheng Yin said with a smile. Cheng Yin’s company is called Miller Mifan Fashion Company, which was established in Hangzhou in the second half of 2014 and entered Shanghai at the end of 2016 to set up a marketing center. Cheng Yin is the first employee. "Fortunately, our founder has long heard of WEWORK and decided to rent it through WEWORK."

  Online application, on-site viewing, the office of WEWORK Yanping Road attracted Cheng Yin at once: a relaxing office environment, a seat for rent. "It suits me perfectly. As long as I rent a seat, I don’t have to worry about other things anymore!" Cheng Wei said.

  Cheng Yin rents a seat for more than 3,000 yuan per month, which sounds expensive at first glance. "However, it is still very cost-effective. I only paid a seat fee, but the meeting room and WiFi are free, the tea and coffee in the tea room are free to drink, and each person can have 120 pages of printing opportunities every month, and the electricity and property fees are also free. More importantly, I don’t have to consider renting an office, decorating and buying furniture. How much time has I saved! "

  The WEWORK rented by Cheng Yin is located in Jing ‘an District, Shanghai, and the daily rent per square meter of the commercial building is 8-mdash; 10 yuan. "But WEWORK makes it easy for a startup to enter the city center!" Member companies can add seats as needed. In less than two months, Cheng Yin, who keeps recruiting new employees, has applied for a quadruple room.

  Interestingly, individuals can also rent a "farewell dinner" or "mobile station" at WEWORK. "Most of these people are lawyers, accountants, consultants, etc. Their working hours are not fixed and they can come at any time." The staff introduced.

  Community-oriented

  ■ Share global resources and connect with the international market to form a win-win situation.

  WEWORK originated in the United States, but because China investment company &mdash; &mdash; Hony Capital invested in its US headquarters and joined the board of directors, and its development in China has obviously accelerated.

  In just over a year, WEWORK has taken root in Shanghai, entered Hong Kong and Beijing, and has 8 office buildings all over the country. In Hong Kong, the first WEWORK building in Causeway Bay was nearly 80% as soon as it opened. In Shanghai, the East China Sea Center, which is about to open, has not yet opened, and there is a big customer &hellip; &hellip;

  Although the supply of commercial buildings in Shanghai has exceeded the demand, shared office is favored for reducing costs. For example, joining a member rental station in WEWORK saves 30% compared with renting an office independently & mdash; 40% of the cost and the working environment is comfortable.

  The most important reason lies in its "communization" and "communization". Members enjoy not only seats and public spaces, but also global resources: members can find seats in WEWORK buildings in any country and any city for free, and they can also communicate with 100,000 members around the world at any time to gain potential customers or fans.

  Cogobuy is an intelligent hardware platform company founded three years ago. Its net name is "Hard Egg" and it has rented 34 workstations in WEWORK. "We hope that through this platform, we can meet international partners and communicate and cooperate with other international members." Zhang Wenzhao of Ketong Core City said.

  In today’s economic globalization, the connection between international markets is particularly important for many companies. Zhao Linghuan, chairman and CEO of Hony Capital, explained: "It will cost a lot to find someone to design, manufacture, develop and reuse in new york, but if this demand is placed in WEWORK’s online community, it is possible to find a low-cost supplier as far away as Shanghai. On the contrary, so do members in Shanghai. This has formed a win-win situation. "

  The rise of local sharing

  ■ With the increasing diversity of modes, enterprises can have more suitable choices.

  Fang Ming and a group of Peking University people founded the "three-care talents" who specialize in recruitment, and settled in the sugar town where they worked together; Teddy (Shanghai) E-commerce Company founded by Yao Zongchang mainly serves people who dry clean clothes, and chose Zhongchuang Space in the Science Park of Shanghai University of Engineering Science to develop from several workstations to more than 500 workstations &hellip; &hellip; WEWORK is not the only way to share office in Shanghai.

  Drawing on WEWORK’s model, many shared office spaces have emerged in China, and sugar cube towns and clubs have grown rapidly.

  Wan Li Jiang, the founder of Sugar Cube Town, said: "WEWORK is the founder of the shared office model. There are many aspects that we are difficult to learn, but the shared office space created locally is also unique."

  At present, there are generally three ways to share office: creating space, accelerator and joint office. "Many of Zhongchuang Space and Accelerators are start-ups, even in their infancy. Many companies enjoy free workstations and enjoy different services according to different growth progress. Some workstations are properly charged, and they may get more investment because of their development and growth. The main mode of joint shared office is the paid workstation and the public space outside the seat. "

  WEWORK has many mobile stations, and Sugar Cube Town intends to reduce the number of mobile stations. "Most China members still pay attention to privacy. We are more fixed rooms and are very popular. Also, WEWORK provides free beer, while managers in China don’t want employees to drink alcohol during work, which is basically not provided. " Wan Li Jiang said.

  No matter how differentiated, local shared office is also trying to reduce the cost of entering enterprises. Wan Li Jiang said, "We regard all the resident members as a team and concentrate on purchasing services. One or two small businesses have no bargaining power, and when we talk about the whole sugar cube town, we talk about the price and the business cost will come down. "

  Save social costs

  ■ Accelerate the establishment and growth of entrepreneurial and innovative enterprises and create more development opportunities.

  It’s not just companies that are losing costs. WEWORK investors told reporters a new phenomenon. After the opening of WEWORK’s shared office building in Causeway Bay, Hong Kong, a large number of entrepreneurial youths unexpectedly welcomed. Previously, there were few entrepreneurs in Hong Kong. One of the important reasons was that the cost of office business in Hong Kong was too high, and the sharing mode gave young people the opportunity to enter the metropolitan center to work hard.

  Gong Yan, a professor at China Europe International Business School, believes that the test of the shared office model depends on whether it improves the efficiency of business transactions and reduces transaction costs. Judging from the current situation, shared office is of great significance to these two aspects. With the prosperity of e-commerce, more and more businesses have begun to adjust and absorb more new enterprises and new models through the shared office model to enhance the vitality of the city.

  Luo Shanying, Party Secretary and Deputy General Manager of Shanghai Zizhu High-tech Zone, said that sharing office reduces the business cost of enterprises, which is just an account of enterprises. More importantly, shared office has accelerated the establishment and growth of entrepreneurial and innovative enterprises, created more development opportunities for society, and reduced more consumption at the same time. This social cost account is more valuable.

  ■ Reporter’s Notes

  Cost reduction needs model innovation.

  Just because of the change of office form, new development opportunities have been created and the cost problem has been alleviated to some extent.

  Reducing costs and increasing efficiency is an eternal proposition in economic development and enterprise operation. This is especially true in the critical period of economic transformation. Lowering the cost a little may bring one more opportunity, a new growth point, or even a new growth pole.

  However, cost reduction will not happen naturally. In addition to the government’s decentralization, it is also necessary to tap wisdom and find more paths. Shared office is an innovation of market model, which allows more people to obtain better office resources and market resources at lower cost. This makes people firmly believe that reducing costs also requires model innovation.

Sawajiri Erika’s endorsement fee exposes half-naked and attracts gold only to enter Hollywood.

        Sawajiri Erika, an actress, attended the press conference of Gaoye Youli beauty brand endorsement, which attracted about 250 reporters to report. Apart from the naked scale of the advertisement, she was once "banned" by the firm last year, and now her advertising value is another focus.

  Before being fired last year, Ying Longhua was one of the spokespersons of kanebo, a well-known Japanese cosmetic brand. According to the person in charge of a well-known advertising company, "the endorsement fee of a well-known cosmetic company is between 30 million and 50 million yen, which is subdivided into 7 million and 80 million yen according to the artist’s debut time, popularity and whether he is a TV drama star. However, advertisers also put many additional conditions on artists, including prohibiting scandals, tanning and tattooing.

  This time, some media reported that Ying Longhua’s salary was around "200 million yen", considering that she is only 23 years old &mdash; &mdash; It is still a "Ruoshou" actress, and people in the circle think that "it will not reach the figure of 100 million units" and "it should be around 50 million yen, and now the economy is in recession".

  At the press conference, the representative of Gaoye Youli Club said that "Yinglong Hua didn’t ask for the film fee, and the two sides reached a consensus readily on the endorsement fee". It is understood that Yinglong Hua is willing to "condescend" to accept the low-cost film fee in order to prepare for the future entry into Hollywood. "Now, the living expenses in Spain with her husband, the huge burden of attending English and performing courses, etc., all need to reserve funds in advance."

  The selection of spokespersons for Gaoye Youli brand has always been controversial. In the 1990s, Seiko Matsuda, who was deeply involved in the scandal, and Ryoko Yonekura &hellip, who broke up with Kabuki actor Ichikawa Ebizou shortly; &hellip; Several times caused a sensation in the world.

  A well-known brand company, which has always been a "sworn enemy" with Takano Tomori, is not to be outdone. In order to compete with its "topical spokesperson", during the World Cup, Beckhams, beauty skier Uemura Aiko and even Kimura Takuya of national group SMAP were invited to appear in advertisements.

  In addition, it is worth mentioning that it is still unknown whether the adventure of launching Yinglong Hua, which is famous for its arrogance, will be a "loss-making business", because Yinglong Hua, who made it public at the press conference and will not withdraw the "six rules for interviewing" sent to major media before, will continue to be treated coldly by TV stations, newspapers and other media in the future. In an interview with the weekly magazine, the person in charge of Takano Youli admitted that "when Yinglong Hua was announced as the brand’s new spokesperson, it received 100 complaints from customers". Whether Yinglonghua can "generate income" for the brand can only be seen.

More wonderful pictures on the next page

Report: the number of netizens reached 829 million, and the Internet penetration rate was 59.6%.

  On February 28th, 2019, China Internet Network Information Center (CNNIC) released the 43rd Statistical Report on Internet Development in China. The report focuses on five aspects: Internet infrastructure, Internet application development, government application development, industrial and technological development and Internet security, and strives to comprehensively reflect the development of China’s Internet in 2018 through multi-angle and all-round data display.

  The amount of basic resources has steadily increased, and IPv6 has broad application prospects.

  As of December 2018, the number of IPv6 addresses in China was 41,079 /32, with an annual growth rate of 75.3%; The total number of domain names is 37.928 million, of which the total number of ".CN" domain names is 21.243 million, accounting for 56.0% of the total number of domain names. In terms of IPv6, China is continuously promoting the large-scale deployment of IPv6, further standardizing the IPv6 address allocation and traceability mechanism, effectively improving the IPv6 security capability, and thus promoting the comprehensive application of IPv6; In terms of domain names, in 2018, China’s high-performance domain name resolution technology continued to develop, new breakthroughs were made in the research and development of independent intellectual property software, and the ability to localize and customize domain name service security policies was further enhanced, thus significantly improving the service capability and security guarantee capability of China’s domain name service system.

  The Internet penetration rate is close to 60%, and the access threshold is further lowered.

  By December 2018, the number of Internet users in China had reached 829 million, with a penetration rate of 59.6%, up 3.8 percentage points from the end of 2017, with 56.53 million new Internet users. The number of mobile Internet users in China reached 817 million, and the proportion of Internet users accessing through mobile phones reached 98.6%, with 64.33 million new mobile Internet users in the whole year. In 2018, the internet coverage was further expanded, and the "last mile" of network infrastructure in poverty-stricken areas was gradually opened.

  The "digital divide" has been bridged quickly; Mobile traffic charges have dropped sharply, and inter-provincial "roaming" has become history, the threshold for residents to access the network has been further lowered, and the efficiency of information exchange has been improved.

  The first law in the field of e-commerce was promulgated, and the industry accelerated the conversion of kinetic energy.

  As of December 2018, the number of online shopping users in China reached 610 million, with an annual growth rate of 14.4% and a utilization rate of 73.6%. The first law in the field of electronic commerce, the Electronic Commerce Law of the People’s Republic of China, was officially promulgated, which is of great significance to promoting the sustained and healthy development of the industry. After years of rapid development, the online consumer market has gradually entered the development stage of upgrading, and the "double upgrade" at both ends of supply and demand is becoming a new round of driving force for industry growth. On the supply side, online and offline resources are accelerating integration, and new models such as social e-commerce and quality e-commerce continue to enrich consumption scenarios and drive the transformation and upgrading of the retail industry; Technologies such as big data and blockchain are deeply applied to effectively improve operational efficiency. On the demand side, the trend of consumption upgrading remains unchanged, and the characteristics of consumption stratification are increasingly prominent, further promoting market diversification.

On January 16th, in Wuma Commercial Street, Lucheng District, Wenzhou City, Zhejiang Province, shoppers paid by "brushing their faces". Photo courtesy/vision china

  Offline payment habits continued to consolidate, and the international payment market accelerated.

  By the end of December 2018, the number of mobile internet payment users in China reached 583 million, with an annual growth rate of 10.7%, and the utilization rate of mobile internet users reached 71.4%. The habit of offline online payment continued to consolidate, and the proportion of netizens using mobile phone online payment increased from 65.5% at the end of 2017 to 67.2%. In terms of cross-border payment, Alipay and WeChat payment have been accessed in compliance in more than 40 countries and regions respectively; In terms of overseas localized payment, Chinese enterprises have operated localized digital wallet products in nine Asian countries and regions.

  Internet entertainment has entered a standardized development track, and the utilization rate of short video users is nearly 80%

  By December 2018, the number of users of online video, online music and online games was 612 million, 576 million and 484 million, respectively, and the utilization rates were 73.9%, 69.5% and 58.4%, respectively. Major online video platforms pay attention to the improvement of program content quality, and self-made content moves towards quality. With the deepening of copyright cooperation among online music enterprises, the process of copyright legalization of digital music has been significantly accelerated. More and more game companies have begun to focus on overseas business, and the influence of domestic games in overseas markets has further expanded. The number of short video users reached 648 million, and the user utilization rate was 78.2%. With the deployment of short videos by many Internet companies, the market maturity gradually improved, and the professionalism and verticality of content production deepened, and high-quality content became the core competitiveness of each platform.

  The efficiency of online government services has been improved, and the people-oriented development concept has been practiced.

  As of December 2018, the number of online government service users in China reached 394 million, accounting for 47.5% of the total netizens. By the end of December 2018, there were 17,962 government websites in China, and the cumulative number of users of WeChat city service reached 570 million. The number of government agencies Weibo certified by Sina platform reached 138,253, and 78,180 government headlines were opened by party and government organs at all levels … In 2018, China’s "Internet+government services" deepened, and governments at all levels relied on the online government service platform to promote online and offline integration. Real-time import of online declaration, queuing appointment, examination and approval results and other information, strengthen the construction of a national unified and multi-level interconnected data sharing and exchange platform, and realize "people running less errands" by "letting data run more". At the same time, all localities have successively started the construction of county-level media integration centers, including all media units such as county radio and television stations, county party newspapers and county-owned websites, and taking charge of all information publishing services in the county, so as to realize centralized and unified management of resources, high-quality information and standardized service, better convey government information and serve the local people.

On June 30, 2018, Dandong, Liaoning Province, fans who rushed to the scene to watch the live broadcast of Modern Brothers crowded Anton Old Street. Photo courtesy/vision china

  The emerging technology field maintains a good development momentum and opens up a new situation in building a network power.

  In 2018, China’s development momentum in basic resources, 5G, quantum information, artificial intelligence, cloud computing, big data, blockchain, virtual reality, Internet of Things logo, supercomputing and other fields is improving. In the field of 5G, breakthroughs have been made in the research and development of core technologies, and government and enterprises have joined forces to promote the steady development of the industry; In the field of artificial intelligence, the ability of scientific and technological innovation has been strengthened, and local plans and policies have been promulgated one after another, effectively promoting the deep integration of artificial intelligence and economic and social development; In the field of cloud computing, the Chinese government attaches great importance to the development of a new generation of information industry represented by it, enterprises actively promote strategic layout, and cloud computing services have gradually been recognized and accepted by the domestic market.

  interlinkage

  Basic data (as of December 2018)

  The number of netizens reached 829 million, with 56.53 million new netizens in the whole year, and the Internet penetration rate was 59.6%, an increase of 3.8 percentage points over the end of 2017.

  The number of mobile phone users reached 817 million, with 64.33 million new mobile phone users in the whole year.

  The number of rural netizens reached 222 million, accounting for 26.7% of the total netizens, an increase of 12.91 million compared with the end of 2017, with a growth rate of 6.2%; The Internet penetration rate in rural areas was 38.4%, up 3.0 percentage points from the end of 2017.

  98.6% netizens use mobile phones to surf the Internet, 48.0% use desktop computers and 35.9% use notebook computers, and 31.1% use TV to surf the Internet.

  The number of IPv6 addresses is 41,079 blocks /32, an increase of 75.3% compared with the end of 2017. The total number of ".CN" domain names is 21.243 million, an increase of 1.9% compared with the end of 2017, accounting for 56.0% of the total number of domain names in China. China’s international export bandwidth is 8,946,570Mbps, with an annual growth rate of 22.2%.

  The number of instant messaging users reached 792 million, and the proportion of netizens was 95.6%.

  Mobile instant messaging users reached 780 million, accounting for 95.5% of mobile Internet users.

  The number of online news users reached 675 million, an increase of 4.3% compared with the end of 2017, and the proportion of netizens used was 81.4%;

  The number of news users on mobile phone network reached 653 million, accounting for 79.9% of mobile phone users, with an annual growth rate of 5.4%.

  The number of online shopping users reached 610 million, an increase of 14.4% compared with the end of 2017, and the proportion of netizens was 73.6%;

  The number of mobile online shopping users reached 592 million, accounting for 72.5% of mobile internet users, with an annual growth rate of 17.1%.

  The number of online takeaway users reached 406 million, an increase of 18.2% compared with the end of 2017, and the proportion of netizens was 49.0%;

  The number of mobile phone online take-out users reached 397 million, accounting for 48.6% of mobile phone users, with an annual growth rate of 23.2%.

  The number of online payment users reached 600 million, an increase of 13.0% compared with the end of 2017, and the proportion of netizens used was 72.5%;

  The scale of mobile phone network payment users reached 583 million, accounting for 71.4% of mobile phone netizens, with an annual growth rate of 10.7%.

  The number of online video users reached 612 million, an increase of 33.09 million compared with the end of 2017, accounting for 73.9% of the total netizens;

  The number of mobile phone network video users reached 590 million, an increase of 41.01 million compared with the end of 2017, accounting for 72.2% of mobile phone netizens.

  The number of short video users reached 648 million, and the proportion of netizens was 78.2%.

  The number of online government service users reached 394 million, accounting for 47.5% of the total netizens.